Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton.
S Valitutti, M Dessing, K Aktories, H Gallati… - The Journal of …, 1995 - rupress.org
Using antigen-specific T cell clones and peptide-pulsed antigen-presenting cells (APCs) we
investigated the mechanisms that lead to sustained signaling, known to be required for …
investigated the mechanisms that lead to sustained signaling, known to be required for …
T cells involved in psoriasis vulgaris belong to the Th1 subset
…, W Jochum, E Hermann, M Girndt, H Gallati… - Journal of Investigative …, 1994 - Elsevier
Although the pathogenesis of psoriasis vulgaris is still unknown, several characteristics point
to an immunologically mediated process. Epidermal psoriatic lesions are characterized by …
to an immunologically mediated process. Epidermal psoriatic lesions are characterized by …
Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and …
…, SB Corradin, R Chiolero, B Yersin, H Gallati… - Critical care …, 1997 - journals.lww.com
Objectives To determine and compare the respective concentrations of tumor necrosis factor
(TNF)-alpha, interleukin (IL)-6, soluble TNF receptors, nitrite/nitrate (NO 2 sup-/NO 3 sup-), …
(TNF)-alpha, interleukin (IL)-6, soluble TNF receptors, nitrite/nitrate (NO 2 sup-/NO 3 sup-), …
Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees.
…, ER De Groot, J Jansen, H Gallati… - The Journal of …, 1994 - rupress.org
The role of interleukin 6 (IL-6) in the toxic sequelae of sepsis is controversial. To assess the
part of IL-6 in inflammatory responses to endotoxin, we investigated eight chimpanzees after …
part of IL-6 in inflammatory responses to endotoxin, we investigated eight chimpanzees after …
Interleukin-6: a sensitive parameter for the early diagnosis of neonatal bacterial infection
…, J Bundschu, P Bartmann, F Pohlandt, H Gallati - Pediatrics, 1994 - publications.aap.org
Objective. Early recognition is important for the successful treatment and outcome of neonatal
infections. As interleukin-6 (Il-6) plays a critical role in the induction of C-reactive protein (…
infections. As interleukin-6 (Il-6) plays a critical role in the induction of C-reactive protein (…
Evaluation of interleukin-6 and soluble receptors of tumor necrosis factor for early diagnosis of neonatal infection
J Messer, D Eyer, L Donato, H Gallati, J Matis… - The Journal of …, 1996 - Elsevier
OBJECTIVE: To evaluate plasma levels of interleukin-6 (IL-6) and soluble tumor necrosis
factor receptors (sTNF-R) 55 and 75 in neonates as a contribution to the early diagnosis of …
factor receptors (sTNF-R) 55 and 75 in neonates as a contribution to the early diagnosis of …
Release of anti-inflammatory mediators after mechanical trauma correlates with severity of injury and clinical outcome
…, M Bonaccio, U Steckholzer, H Gallati… - Journal of Trauma …, 1995 - journals.lww.com
Excessive synthesis of proinflammatory cytokines [tumor necrosis factor (TNF)-alpha and
interleukin (IL)-1beta] after trauma has been correlated with poor outcome. Recently, naturally …
interleukin (IL)-1beta] after trauma has been correlated with poor outcome. Recently, naturally …
[HTML][HTML] Recombinant 55-kDa tumor necrosis factor (TNF) receptor. Stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity.
…, EJ Schlaeger, M Brockhaus, H Gallati… - Journal of Biological …, 1991 - Elsevier
The extracellular domain of the 55-kDa TNF receptor (rsTNFR beta) has been expressed as
a secreted protein in baculovirus-infected insect cells and Chinese hamster ovary (CHO)/dhfr…
a secreted protein in baculovirus-infected insect cells and Chinese hamster ovary (CHO)/dhfr…
Exogenous glutamine requirement is confined to late events of T cell activation
…, L Filgueira, R Babst, H Gallati… - Journal of cellular …, 1993 - Wiley Online Library
Glutamine is required for the proliferation of lymphocytes, but quantitative effects on discrete
steps of activation remain unknown to date. Therefore the influence of glutamine (range: 0 …
steps of activation remain unknown to date. Therefore the influence of glutamine (range: 0 …
Differential expression of proinflammatory cytokines and their inhibitors during the course of meningococcal infections
…, R van Dalen, RW Sauerwein, H Gallati… - Journal of Infectious …, 1994 - academic.oup.com
Circulating concentrations of tumor necrosis factor-α (TNF), interleukin (IL)-1β, IL-6, IL-1
receptor antagonist (IL-1ra), and soluble TNF receptors p55 (sTNFr-55) and p75 (sTNFr-75) and …
receptor antagonist (IL-1ra), and soluble TNF receptors p55 (sTNFr-55) and p75 (sTNFr-75) and …