Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan
H Kumada, T Okanoue, M Onji, H Moriwaki… - Hepatology …, 2010 - Wiley Online Library
In the 2008 guidelines for the treatment of patients with cirrhosis, who are infected with
hepatitis B virus (HBV), the main goal is to normalize levels of alanine and aspartate …
hepatitis B virus (HBV), the main goal is to normalize levels of alanine and aspartate …
[HTML][HTML] Phase Ib study of lenvatinib plus pembrolizumab in patients with unresectable hepatocellular carcinoma
…, T Okusaka, M Kobayashi, H Kumada… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
PURPOSE The immunomodulatory effect of lenvatinib (a multikinase inhibitor) on tumor
microenvironments may contribute to antitumor activity when combined with programmed death …
microenvironments may contribute to antitumor activity when combined with programmed death …
[HTML][HTML] Gene expression in fixed tissues and outcome in hepatocellular carcinoma
…, J Bruix, SL Friedman, H Kumada… - … England Journal of …, 2008 - Mass Medical Soc
Background It is a challenge to identify patients who, after undergoing potentially curative
treatment for hepatocellular carcinoma, are at greatest risk for recurrence. Such high-risk …
treatment for hepatocellular carcinoma, are at greatest risk for recurrence. Such high-risk …
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
…, G Watanabe, S Gabriel, SL Friedman, H Kumada… - Cancer research, 2009 - AACR
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to
develop genomic-based classification for HCC have yielded highly divergent results, …
develop genomic-based classification for HCC have yielded highly divergent results, …
[PDF][PDF] The long‐term pathological evolution of chronic hepatitis C
M Yano, H Kumada, M Kage, K Ikeda… - …, 1996 - Wiley Online Library
Most patients infected with hepatitis C virus (HCV) develop chronic hepatitis. Unfortunately,
the pathological evolution of this disease over time is not completely understood. We studied …
the pathological evolution of this disease over time is not completely understood. We studied …
[PDF][PDF] Long‐term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection
…, Y Arase, K Ikeda, M Kobayashi, H Kumada - …, 2013 - Wiley Online Library
Chronic hepatitis B virus (HBV) infection leads to cirrhosis and hepatocellular carcinoma (HCC).
Antiviral agents are thought to reduce HCC development, but agents such as …
Antiviral agents are thought to reduce HCC development, but agents such as …
Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection
H Kumada, Y Suzuki, K Ikeda, J Toyota, Y Karino… - Hepatology, 2014 - journals.lww.com
All-oral combinations of direct-acting antivirals may improve efficacy and safety outcomes
for patients with hepatitis C virus (HCV) infection, particularly those who are poor candidates …
for patients with hepatitis C virus (HCV) infection, particularly those who are poor candidates …
Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma
…, T Takayama, JH Yoon, T Hori, H Kumada… - European journal of …, 2011 - Elsevier
BACKGROUND: In Japan and South Korea, transarterial chemoembolisation (TACE) is an
important locoregional treatment for patients with unresectable hepatocellular carcinoma (…
important locoregional treatment for patients with unresectable hepatocellular carcinoma (…
Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis
…, K Higuchi, S Nishiguchi, H Kumada… - Clinical …, 2005 - Elsevier
Background & Aims: Nutritional intervention with branched-chain amino acid (BCAA) is
reported to increase serum albumin concentration in patients with decompensated cirrhosis. …
reported to increase serum albumin concentration in patients with decompensated cirrhosis. …
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians
…, M Kubo, T Tsunoda, N Kamatani, H Kumada… - Nature …, 2009 - nature.com
Chronic hepatitis B is a serious infectious liver disease that often progresses to liver
cirrhosis and hepatocellular carcinoma; however, clinical outcomes after viral exposure vary …
cirrhosis and hepatocellular carcinoma; however, clinical outcomes after viral exposure vary …