[HTML][HTML] Skin barrier abnormalities and immune dysfunction in atopic dermatitis
Atopic dermatitis (AD) is a common and relapsing skin disease that is characterized by skin
barrier dysfunction, inflammation, and chronic pruritus. While AD was previously thought to …
barrier dysfunction, inflammation, and chronic pruritus. While AD was previously thought to …
[HTML][HTML] Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives
Mitochondrial targeting is a promising approach for solving current issues in clinical application
of chemotherapy and diagnosis of several disorders. Here, we discuss direct conjugation …
of chemotherapy and diagnosis of several disorders. Here, we discuss direct conjugation …
Dose‐linear pharmacokinetics of oleanolic acid after intravenous and oral administration in rats
…, WR Choi, SM Lee, CK Han, HS Lee - … & drug disposition, 2007 - Wiley Online Library
The pharmacokinetics of oleanolic acid was evaluated in vitro and in vivo. From Caco‐2 cell
permeation studies, oleanolic acid was a low permeability compound with no directional …
permeation studies, oleanolic acid was a low permeability compound with no directional …
[HTML][HTML] Mitochondria-targeted drug delivery in cancers
H Cho, YY Cho, MS Shim, JY Lee, HS Lee… - Biochimica et Biophysica …, 2020 - Elsevier
Mitochondria are considered one of the most important subcellular organelles for targeting
and delivering drugs because mitochondria are the main location for various cellular …
and delivering drugs because mitochondria are the main location for various cellular …
[HTML][HTML] Mitochondrial-targeting anticancer agent conjugates and nanocarrier systems for cancer treatment
G Battogtokh, YY Cho, JY Lee, HS Lee… - Frontiers in …, 2018 - frontiersin.org
The mitochondrion is an important intracellular organelle for drug targeting due to its key
roles and functions in cellular proliferation and death. In the last few decades, several studies …
roles and functions in cellular proliferation and death. In the last few decades, several studies …
[HTML][HTML] Therapeutic regulation of the NLRP3 inflammasome in chronic inflammatory diseases
Inflammasomes are cytosolic pattern recognition receptors that recognize pathogen-associated
molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs) …
molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs) …
Pharmacokinetics of a ginseng saponin metabolite compound K in rats
…, SA Kim, DH Sohn, JB Kim, HS Lee - … & drug disposition, 2006 - Wiley Online Library
The absorption, dose‐linearity and pharmacokinetics of compound K, a major intestinal
bacterial metabolite of ginsenosides, were evaluated in vitro and in vivo. Using the Caco‐2 cell …
bacterial metabolite of ginsenosides, were evaluated in vitro and in vivo. Using the Caco‐2 cell …
[HTML][HTML] Mechanism investigation of rifampicin-induced liver injury using comparative toxicoproteomics in mice
… Sangkyu Lee analyzed the data; Tae Won Jeon, Sung Hwan Ki and Hye Suk Lee contributed
reagents/materials/analysis tools; Ju-Hyun Kim, Woong Shik Nam and Sangkyu Lee wrote …
reagents/materials/analysis tools; Ju-Hyun Kim, Woong Shik Nam and Sangkyu Lee wrote …
[HTML][HTML] Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells
… Hye Suk Lee … Hye Suk Lee … Gabsik Yang, Han Chang Kang, Yong-Yeon Cho, and
Hye Suk Lee participated in a part of the experiments and analyzed a part of the data. Joo Y. …
Hye Suk Lee participated in a part of the experiments and analyzed a part of the data. Joo Y. …
Simultaneous determination of aceclofenac and diclofenac in human plasma by narrowbore HPLC using column-switching
HS Lee, CK Jeong, SJ Choi, SB Kim, MH Lee… - … of pharmaceutical and …, 2000 - Elsevier
A fully automated narrowbore high performance liquid chromatography (HPLC) with column-switching
was developed for the simultaneous determination of aceclofenac and diclofenac …
was developed for the simultaneous determination of aceclofenac and diclofenac …