Metabolism and excretion of an oral taxane analog,[14C] 3′-tert-butyl-3′-N-tert-butyloxycarbonyl-4-deacetyl-3′-dephenyl-3′-N-debenzoyl-4-O-methoxy-paclitaxel …

…, D Zhang, WG Humphreys, IV Ekhato… - Drug metabolism and …, 2009 - ASPET
3′-tert-Butyl-3′-N-tert-butyloxycarbonyl-4-deacetyl-3′-dephenyl-3′-N-debenzoyl-4-O-methoxy-paclitaxel
(BMS-275183) is a taxane analog that has the potential for oral use in the …

Metabolism and disposition of [14C] BMS-690514 after oral administration to rats, rabbits, and dogs

H Hong, H Su, H Sun, A Allentoff, IV Ekhato… - Drug metabolism and …, 2010 - ASPET
(3R,4R)-4-Amino-1-((4-((3-methoxyphenyl)amino)pyrrolo[2,1-f] [1,2,4]triazin-5-yl)methyl)-3-piperidinol
(BMS-690514) is a potent inhibitor of human epidermal growth factor receptors 1, 2…

Synthesis of [13C4]Baraclude® (entecavir)

SB Tran, IV Ekhato, JK Rinehart - Journal of Labelled …, 2009 - Wiley Online Library
Entecavir, labeled as 1H‐[ 13 C 4 ]purin‐6(9H)‐one, was prepared from commercially
available [ 13 C]guanidine HCl, 1 and diethyl [1,2,3‐ 13 C 3 ]malonate, 2. The reagents were …

[BOOK][B] Partial Synthesis of Steroids Related to Brassinolide

IV Ekhato - 1982 - search.proquest.com
Brassinolide-isolated from extracts of Brassica napus L.(rape) pollen-is the first known steroid
capable of producing novel growth effects in plants. The structure and stereochemistry, …

[CITATION][C] Metabolism and excretion of an oral taxane analog,[14C] BMS-275183, in rats and dogs

…, D Zhang, WG Humphreys, IV Ekhato… - Drug Metabolism and …, 2009 - ASPET
BMS-275183 is a taxane analog that has the potential for oral use in the treatment of various
cancer types. In this study, the metabolism and excretion of [ 14 C] BMS-275183 were …

Isotope labeled 'HEA Moiety'in the synthesis of labeled HIV‐protease inhibitors–Part 1

IV Ekhato, Y Liao, M Plesescu - Journal of Labelled …, 2004 - Wiley Online Library
[(S)‐1′‐((N‐tert‐Butyloxycarbonyl)amino)‐2S‐[ 2 H 5 ]phenyl‐ethyl]oxirane 11, made from
[ 2 H 5 ]‐bromobenzene, was transformed into the HIV‐protease inhibitors [ 2 H 5 ]‐DPH …

Isotope labeled 'HEA/HEE'moiety in the synthesis of labeled HIV‐protease inhibitors—Part II

IV Ekhato, Y Liao, M Plesescu - Journal of Labelled …, 2005 - Wiley Online Library
[ 2 H 5 ]‐Amprenavir and [ 2 H 5 ]‐saquinavir have been prepared from a common labeled
precursor (1S, 2S)‐(1‐oxiranyl‐2‐[ 2 H 5 ]phenylethyl)‐carbamic acid tert‐butyl ester, 1. Both …

[CITATION][C] Metabolism of the taxane analog [C-14] BMS-275183 following oral administration to rats and dogs

…, WG Humphreys, IV Ekhato - DRUG …, 2006 - … & FRANCIS INC 325 CHESTNUT ST …

[CITATION][C] Mass Balance and Metabolism of the Taxane Analog [C-14] BMS-275183 Following Oral Administration to Humans

…, VT Ly, IV Ekhato… - DRUG …, 2010 - … TELEPHONE HOUSE, 69-77 PAUL …