… Nunes, unpublished observations), which suggests that LTBP is covalently linked to the
matrix. Work by our laboratory suggests that this cross-linking may be mediated by the enzyme …

Transforming growth factor-β (TGF-β) is secreted by many cell types as part of a large latent
complex composed of three subunits: TGF-β, the TGF-β propeptide, and the latent TGF-β …

Objectives : The study sought to test whether high-dose statin treatment would result in
greater reductions in plaque inflammation than low-dose statins, using fluorodeoxyglucose-…

Transforming growth factor (TGF-)β is secreted as a latent complex in which the mature growth
factor remains associated with its propeptide. In order to elicit a biological response, the …

Dopaminergic (DA) neurons of substantia nigra in the midbrain control voluntary movement,
and their degeneration is the cause of Parkinson's disease. The complete set of genes …

Transforming growth factor-beta (TGF-beta) is secreted by most cells as a biologically inactive
complex, called the large latent TGF-beta complex. The complex is comprised of latent …

In humans, creatinine is formed by a multistep process in liver and muscle and eliminated
via the kidney by a combination of glomerular filtration and active transport. Based on current …

The defense of the ocular surfaces presents an unique challenge in that not only must integrity
be maintained against microbial, inflammatory and physical assault, but it must be done …

Evidence suggests that the plasminogen activators (PAs), in particular urokinase-type PA (uPA),
play a pivotal role in tumor invasion and metastasis. We studied the contribution of the …

The vertebrate lens is a relatively simple cellular structure that has evolved to refract light. The
ability of the lens to focus light on the retina derives from a number of properties including …