[HTML][HTML] Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer

IJ Létourneau, MCJ Quinn, LL Wang, L Portelance… - BMC cancer, 2012 - Springer
Background Cell line models have proven to be effective tools to investigate a variety of ovarian
cancer features. Due to the limited number of cell lines, particularly of the serous subtype…

[HTML][HTML] RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 are new prognostic biomarkers in serous epithelial ovarian cancer

…, E Carmona, V Barres, K Rahimi, IJ Letourneau… - PLoS …, 2014 - journals.plos.org
Purpose Epithelial ovarian cancer has the highest mortality rate of all gynecological
malignancies. We have shown that high RAN expression strongly correlates with high-grade and …

Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1)

IJ Létourneau, RG Deeley… - Pharmacogenetics and …, 2005 - journals.lww.com
The 190-kDa ATP-binding cassette (ABC) multidrug resistance protein 1 (MRP1) encoded
by the MRP1/ABCC1 gene mediates the active cellular efflux of glucuronide, glutathione and …

Functional and Structural Consequences of Cysteine Substitutions in the NH2 Proximal Region of the Human Multidrug Resistance Protein 1 (MRP1/ABCC1)

EM Leslie, IJ Létourneau, RG Deeley, SPC Cole - Biochemistry, 2003 - ACS Publications
The 190 kDa multidrug resistance protein 1 (MRP1; ABCC1) is comprised of three membrane
spanning domains (MSDs) and two nucleotide binding domains (NBDs) configured MSD1-…

Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function

IJ Letourneau, AJ Slot, RG Deeley, SPC Cole - Drug metabolism and …, 2007 - ASPET
The ATP-binding cassette multidrug resistance protein 1 MRP1 (ABCC1) mediates the cellular
efflux of organic anions including conjugated metabolites, chemotherapeutic agents, and …

Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites

IJ Létourneau, RJ Bowers, RG Deeley, SPC Cole - Toxicology letters, 2005 - Elsevier
The human ATP-binding cassette proteins MRP1 (ABCC1), MRP2 (ABCC2) and MRP3 (ABCC3)
are active transporters of antineoplastic drugs as well as conjugated metabolites and …

Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter

IJ Létourneau, A Nakajima, RG Deeley… - Biochemical …, 2008 - Elsevier
The ATP-binding cassette multidrug resistance protein 1 (MRP1) mediates ATP-dependent
cellular efflux of drugs and organic anions. We previously described a mutant, MRP1-…

[DOC][DOC] Mille et une réponses

K de Bellefeuille, J Isabelle - files.aqpehv.net
… Johanne Isabelle … « Après trois ans de questionnements et de recherches, j'ai enfin
découvert l'AQEPHV. J'ai eu l'impression d'avoir gagné le gros lot! Enfin quelqu'un qui peut …

with the requirements for the degree of Doctor of Philosophy

I Létourneau - 2007 - library-archives.canada.ca
The multidrug resistance proteins MRP1, MRP2 and MRP3 mediate ATP-dependent cellular
efflux of a wide variety of compounds including toxicants and chemotherapeutic agents. The …

[BOOK][B] Le territoire dans les veines

JF Létourneau - 2017 - books.google.com
… Dans cet essai, Jean-François Létourneau définit une poétique du territoire inspirée par le
travail d’écrivains autochtones. Ces derniers actualisent dans leurs textes des sensibilités qui …