Global overview of the applications of the Ecopath with Ecosim modeling approach using the EcoBase models repository

M Colléter, A Valls, J Guitton, D Gascuel, D Pauly… - Ecological …, 2015 - Elsevier
The ‘Ecopath’, later expanded to ‘Ecopath with Ecosim’ (‘EwE’), modeling approach has been
applied to hundreds of ecosystems around the world, since its first implementation in 1984…

A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability

…, E Despras, JL Jauffret, F Bertucci, J Guitton… - Nature medicine, 2017 - nature.com
Chromosomal instability (CIN), a feature of most adult neoplasms from their early stages
onward, is a driver of tumorigenesis. However, several malignancy subtypes, including some …

Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

M Boissan, G Montagnac, Q Shen, L Griparic, J Guitton… - Science, 2014 - science.org
Dynamin superfamily molecular motors use guanosine triphosphate (GTP) as a source of
energy for membrane-remodeling events. We found that knockdown of nucleoside …

Spatial synchrony in the response of a long range migratory species (Salmo salar) to climate change in the North Atlantic Ocean

…, G Chaput, H Du Pontavice, J Guitton… - Global Change …, 2020 - Wiley Online Library
A major challenge in understanding the response of populations to climate change is to
separate the effects of local drivers acting independently on specific populations, from the effects …

[HTML][HTML] Vitreous humor analysis for the detection of xenobiotics in forensic toxicology: a review

F Bévalot, N Cartiser, C Bottinelli, L Fanton, J Guitton - Forensic toxicology, 2016 - Springer
Vitreous humor (VH) is a gelatinous substance contained in the posterior chamber of the eye,
playing a mechanical role in the eyeball. It has been the subject of numerous studies in …

Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein

…, B Peres, C Gauthier, J Guitton… - Journal of medicinal …, 2012 - ACS Publications
A series of 13 disubstituted chromones was synthesized. Two types of substituents, on each
side of the scaffold, contributed to both the potency of ABCG2 inhibition and the cytotoxicity. …

[HTML][HTML] Estimating fishing effort in small-scale fisheries using GPS tracking data and random forests

F Behivoke, MP Etienne, J Guitton, RM Randriatsara… - Ecological …, 2021 - Elsevier
During the last decade spatial patterns of industrial fisheries have been increasingly
characterized using tracking technologies and machine learning analytical algorithms. In contrast, …

Zones fonctionnelles pour les ressources halieutiques dans les eaux sous souveraineté française. Deuxième partie: Inventaire.

A Regimbart, J Guitton, O Le Pape - 2018 - archimer.ifremer.fr
Suite à l’adoption de la loi pour la reconquête de la biodiversité, de la nature et des
paysages, une nouvelle catégorie d’Aire Marine Protégée, appelée zone de conservation …

[HTML][HTML] Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug …

…, J Cros, C de la Fouchardière, P Dubus, J Guitton… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Solid tumors often display chemotherapy resistance. Pancreatic ductal adenocarcinoma (PDAC)
is the archetype of resistant tumors as current chemotherapies are inefficient. The tumor …

Are we ready to track climate‐driven shifts in marine species across international boundaries?‐A global survey of scientific bottom trawl data

…, H Gislason, M Goren, J Guitton… - Global change …, 2021 - Wiley Online Library
Marine biota are redistributing at a rapid pace in response to climate change and shifting
seascapes. While changes in fish populations and community structure threaten the …