The nonsteroidal anti-inflammatory drug diclofenac causes a rare but potentially fatal
hepatotoxicity that may be associated with the formation of reactive metabolites. In this study, three …

The multidrug resistance protein Mrp2 is an ATP-binding cassette (ABC) transporter mainly
expressed in liver, kidney, and intestine. One of the physiological roles of Mrp2 is to transport …

The pharmacokinetics and hepatic metabolism of [ 3 H] ivermectin (IVM) and [ 3 H]cyclosporin
A (CSA) were investigated in a subpopulation of the CF-1 mouse stock naturally deficient …

The development of potent, orally bioavailable (in rat) and selective dihydroquinazolinone
inhibitors of p38α MAP kinase is described. These analogues are hybrids of a …

… Twitter account than a member 10 years his or her junior and a 0.09 lower probability of
having a Twitter account than a member 20 years his or her junior. Lastly, seniority is not a good …

OBJECTIVES: The present study sought to examine: (a) the association between depressive
symptoms among pre-menopausal and peri-menopausal women and subsequent difficulty …

Although zomepirac (ZP) and tolmetin (TM) induce anaphylactic reactions and form reactive
acyl glucuronides, a direct link between the two events remains obscure. We report herein …

Purpose The purpose of this paper is to understand why some Senators choose to use
Twitter more frequently than others. Building on past research, which explored causal factors …

Genetically obese Zucker rats exhibit symptoms similar to those of obese patients with
insulin-resistance or Type II diabetes; therefore, they have been used as a genetic model to study …

During the past 15 years, the development of new electronic technologies has altered the
traditional patterns of communication between Members of Congress and constituents. Many …