[HTML][HTML] Small intestinal bacterial overgrowth syndrome

…, M Förstl, S Rejchrt, J Kvetina… - World journal of …, 2010 - ncbi.nlm.nih.gov
Human intestinal microbiota create a complex polymicrobial ecology. This is characterised
by its high population density, wide diversity and complexity of interaction. Any dysbalance of …

[PDF][PDF] Caco-2 cells, biopharmaceutics classification system (BCS) and biowaiver

…, V Stetinova, Z Svoboda, J Kvetina - Acta Medica (Hradec …, 2011 - actamedica.lfhk.cuni.cz
Almost all orally administered drugs are absorbed across the intestinal mucosa. The Caco-2
monolayers are used as an in vitro model to predict drug absorption in humans and to …

Presence and activity of cytochrome P450 isoforms in minipig liver microsomes: comparison with human liver samples

…, I Gut, K Hruby, Z Svoboda, J Kvetina - Drug Metabolism and …, 1998 - ASPET
Cytochrome P450 (CYP) of the 3A family (CYP3A) has been detected in minipig liver microsomes
by immunochemical screening (Western blotting), revealing bands that co-migrate with …

Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T

O Slanař, M Nobilis, J Kvétina, O Matoušková… - European journal of …, 2007 - Springer
Dear Professor Dahlqvist, We have read with interest the articles by Pedersen et al. and
Wang et al. who highlighted the importance of functional polymorphisms of CYP2D6 on the …

[PDF][PDF] Caco-2 cell monolayer integrity and effect of probiotic Escherichia coli Nissle 1917 components

V Stetinová, L Smetanova, J Kvetina… - Neuroendocrinology …, 2010 - nel.altamira.sk
OBJECTIVES: Different probiotic strains used in clinical trials have shown prophylactic
properties in different inflammatory diseases of the gastrointestinal tract. This study was aimed to …

[PDF][PDF] Preclinical electrogastrography in experimental pigs

J Květina, JE Varayil, SM Ali, M Kuneš… - Interdisciplinary …, 2010 - intapi.sciendo.com
Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric
activity or slow waves from cutaneous leads placed over the stomach. This paper provides …

[PDF][PDF] Caco-2 cells and Biopharmaceutics Classification System (BCS) for prediction of transepithelial transport of xenobiotics (model drug: Caffeine)

L Smetanova, V Stetinova, D Kholova, J Kvetina… - Neuroendocrinology …, 2009 - nel.edu
OBJECTIVES: The Caco-2 cell monolayer model is widely used as a standard screening
tool for studying the mechanisms of cellular drug transport. Caffeine was chosen as a model …

Morphometric analysis of the porcine gastrointestinal tract in a 10-day high-dose indomethacin administration with or without probiotic bacteria Escherichia coli Nissle …

J Bures, J Pejchal, J Kvetina, A Tichý… - Human & …, 2011 - journals.sagepub.com
Background: Nonsteroidal anti-inflammatory drugs may cause severe injury to all parts of
the gastrointestinal tract. It has been hypothesised that probiotic bacteria might reduce this …

[HTML][HTML] The effect of general anaesthesia on gastric myoelectric activity in experimental pigs

I Tachecí, J Květina, M Kuneš, M Pavlík… - BMC …, 2013 - Springer
Background Surface electrogastrography (EGG) is a non-invasive method for clinical
assessment of gastric myoelectrical activity. Different forms of general anaesthesia might have …

High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of …

…, Z Svoboda, M Lísa, M Holčapek, J Květina… - … of Chromatography B, 2007 - Elsevier
Galantamine, an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus
woronowii, Amaryllidaceae) and related species, is employed in human medicine for …