Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
ECY Chow, HP Quach, Y Zhang, JZY Wang… - … of Pharmacology and …, 2017 - ASPET
The humanized liver mouse model is being exploited increasingly for human drug metabolism
studies. However, its model stability, intercommunication between human hepatocytes …
studies. However, its model stability, intercommunication between human hepatocytes …
Functional integrity of the chimeric (humanized) mouse liver: enzyme zonation, physiologic spaces, and hepatic enzymes and transporters
ECY Chow, JZY Wang, HP Quach, H Tang… - Drug Metabolism and …, 2016 - ASPET
Chimeric mouse liver models are useful in vivo tools for human drug metabolism studies;
however, liver integrity and the microcirculation remain largely uninvestigated. Hence, we …
however, liver integrity and the microcirculation remain largely uninvestigated. Hence, we …
[HTML][HTML] Self-organizing human cardiac microchambers mediated by geometric confinement
Tissue morphogenesis and organ formation are the consequences of biochemical and
biophysical cues that lead to cellular spatial patterning in development. To model such events in …
biophysical cues that lead to cellular spatial patterning in development. To model such events in …
A planet within the debris disk around the pre-main-sequence star AU Microscopii
…, K von Braun, B Walp, J Wang, SX Wang… - Nature, 2020 - nature.com
AU Microscopii (AU Mic) is the second closest pre-main-sequence star, at a distance of 9.79
parsecs and with an age of 22 million years 1 . AU Mic possesses a relatively rare 2 and …
parsecs and with an age of 22 million years 1 . AU Mic possesses a relatively rare 2 and …
Algorithmics and applications of tree and graph searching
… Jason TL Wang … #"$ & %¤ % % U V2 (¦8 Wq H z tr ¢cI H QE¦ H ¢c (¦8 C$ $¢¥¤§¦ %E XQ£fD
"7 (' fD $ & H $¦ W( ¢&WY¦©H7 H q Hv H (¦s & "¦© q¤(%E (#z Wq H tr ¢&I …
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On the editing distance between undirected acyclic graphs
We consider the problem of comparing CUAL graphs (Connected, Undirected, Acyclic graphs
with nodes being Labeled). This problem is motivated by the study of information retrieval …
with nodes being Labeled). This problem is motivated by the study of information retrieval …
Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma
NK Saxena, PP Fu, A Nagalingam, J Wang, J Handy… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Epidemiological studies have shown that obesity is a risk factor for
hepatocellular carcinoma (HCC). Lower adiponectin levels are associated with poor …
hepatocellular carcinoma (HCC). Lower adiponectin levels are associated with poor …
New techniques for extracting features from protein sequences
In this paper we propose new techniques to extract features from protein sequences. We
then use the features as inputs for a Bayesian neural network (BNN) and apply the BNN to …
then use the features as inputs for a Bayesian neural network (BNN) and apply the BNN to …
Tattoolike polyaniline microparticle-doped gold nanowire patches as highly durable wearable sensors
Wearable and highly sensitive strain sensors are essential components of electronic skin for
future biomonitoring and human machine interfaces. Here we report a low-cost yet efficient …
future biomonitoring and human machine interfaces. Here we report a low-cost yet efficient …
The Gemini Planet Imager Exoplanet Survey: giant planet and brown dwarf demographics from 10 to 100 au
…, RJ De Rosa, B Macintosh, JJ Wang… - The Astronomical …, 2019 - iopscience.iop.org
We present a statistical analysis of the first 300 stars observed by the Gemini Planet Imager
Exoplanet Survey. This subsample includes six detected planets and three brown dwarfs; …
Exoplanet Survey. This subsample includes six detected planets and three brown dwarfs; …