Chiral separation of labetalol stereoisomers in human plasma by capillary electrophoresis

TV Goel, JG Nikelly, RC Simpson… - … of Chromatography A, 2004 - Elsevier
A newly derivatized cyclodextrin [octakis-(2,3-diacetyl-6-sulfato)-γ-cyclodextrin] was investigated
as a chiral selector in capillary zone electrophoresis in a study of the chiral separation …

Determination of ethanol in alcoholic beverages by liquid chromatography using the UV detector

JM Betz, JG Nikelly - Journal of chromatographic science, 1987 - academic.oup.com
Ethanol in certain beverages and in similar solutions may be determined by reversed-phase
liquid chromatography (LC) using the UV detector. The mobile phase in this indirect …

Metabolism of para-aminophenol by rat hepatocytes

Z Yan, JG Nikelly, L Killmer, JB Tarloff - Drug metabolism and disposition, 2000 - ASPET
Autoxidation of para-aminophenol (PAP) has been proposed to account for the selective
nephrotoxicity of this compound. However, other studies suggest that hepatic metabolites of …

Amperometric Titrations of Micromolar Solutions

JG Nikelly, WD Cooke - Analytical Chemistry, 1956 - ACS Publications
Amperometric titrations of dilute solutions of metal ions with disodium ethylenediamine
tetraacetate have been carried out using a mercury pool indicator electrode. Some of the …

Analytical biotechnology: Capillary electrophoresis and chromatography

C Horváth, JG Nikelly - 1990 - osti.gov
The papers describe the separation, characterization, and equipment required for the
electrophoresis or chromatography of cyclic nucleotides, pharmaceuticals, therapeutic proteins, …

Pulse dampening system for high pressure liquid chromatography

DA Ventura, JG Nikelly - Analytical Chemistry, 1978 - ACS Publications
Mechanical reciprocating piston pumps are widely used in high pressure liquid chromatography
(HPLC) owing toseveral advantages, including relatively low cost, constantflow that is …

Pulse dampener for high pressure liquid chromatography

JG Nikelly, DA Ventura - Analytical Chemistry, 1979 - ACS Publications
However, it should be noted thatvirtually all of the new pumps that are specifically designed
for HPLC are of the multiple-head or multiple-action type. In addition, many of the multiple …

Consecutive gas chromatograms from a parallel columns using a single injection and a common detector

PK Gupta, JG Nikelly - Analytical chemistry, 1991 - ACS Publications
A method of two-dimensional chromatography Is described In which two consecutive
chromatograms are obtained In a• Ingle run using two parallel capillary columns connected to a …

Large diameter porous layer open tubular gas chromatography columns

JG Nikelly - Analytical Chemistry, 1976 - ACS Publications
Large diameter, 0.04-in. id, porous-layer open-tubular (PLOT) columns, made by the dynamic
coating procedure, are com-pared with similar columns of smaller id, 0.03 in. Asexpected, …

A pulse-compensating technique for LC instruments

JM Betz, JG Nikelly - Journal of chromatographic science, 1983 - academic.oup.com
A technique is described whereby the pulsations generated by the reciprocating pump are
totally removed from the baseline of the chromatogram. The method takes advantage of the …