User profiles for John J. Stegeman
John StegemanWoods Hole Oceanographic Institution Verified email at whoi.edu Cited by 33534 |
P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature
…, L Koymans, T Kamataki, JJ Stegeman… - Pharmacogenetics …, 1996 - journals.lww.com
We provide here a list of 481 P450 genes and 22 pseudogenes, plus all accession numbers
that have been reported as of October 18, 1995. These genes have been described in 85 …
that have been reported as of October 18, 1995. These genes have been described in 85 …
The Genome of the Sea Urchin Strongylocentrotus purpuratus
…, M Scally, JJ Stegeman, EL Allgood, J Cool… - Science, 2006 - science.org
We report the sequence and analysis of the 814-megabase genome of the sea urchin
Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing …
Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing …
[HTML][HTML] The African coelacanth genome provides insights into tetrapod evolution
The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of
lobe-finned fish was thought to have become extinct 70 million years ago. The modern …
lobe-finned fish was thought to have become extinct 70 million years ago. The modern …
Cytochrome P-450 monooxygenase systems in aquatic species: carcinogen metabolism and biomarkers for carcinogen and pollutant exposure.
JJ Stegeman, JJ Lech - Environmental health perspectives, 1991 - ehp.niehs.nih.gov
High levels of polynuclear aromatic hydrocarbon (PAH) carcinogens commonly occur in aquatic
systems where neoplasms arise in fish and other animals. Enzymes that transform PAHs …
systems where neoplasms arise in fish and other animals. Enzymes that transform PAHs …
[HTML][HTML] Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish
…, T Parente, ME Jönsson, DR Nelson, JJ Stegeman - BMC genomics, 2010 - Springer
Background Increasing use of zebrafish in drug discovery and mechanistic toxicology
demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP enzymes …
demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP enzymes …
[HTML][HTML] Human health and ocean pollution
PJ Landrigan, JJ Stegeman, LE Fleming… - Annals of global …, 2020 - ncbi.nlm.nih.gov
Background: Pollution–unwanted waste released to air, water, and land by human activity–is
the largest environmental cause of disease in the world today. It is responsible for an …
the largest environmental cause of disease in the world today. It is responsible for an …
Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics
…, BB Rees, TD Singer, JJ Stegeman… - … and Physiology Part D …, 2007 - Elsevier
A strong foundation of basic and applied research documents that the estuarine fish Fundulus
heteroclitus and related species are unique laboratory and field models for understanding …
heteroclitus and related species are unique laboratory and field models for understanding …
[HTML][HTML] The Minderoo-Monaco Commission on plastics and human health
…, BJ Seewoo, M Spring, JJ Stegeman… - Annals of Global …, 2023 - ncbi.nlm.nih.gov
Background: Plastics have conveyed great benefits to humanity and made possible some of
the most significant advances of modern civilization in fields as diverse as medicine, …
the most significant advances of modern civilization in fields as diverse as medicine, …
Aryl Hydrocarbon Receptor 2 Mediates 2,3,7,8-Tetrachlorodibenzo-p-dioxin Developmental Toxicity in Zebrafish
…, W Dong, T Hiraga, JJ Stegeman… - Toxicological …, 2003 - academic.oup.com
In order to use the zebrafish as a model vertebrate to investigate the developmental toxicity
of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), it is essential to know whether one or both …
of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), it is essential to know whether one or both …
An alternative 7-ethoxyresorufin O-deethylase activity assay: a continuous visible spectrophotometric method for measurement of cytochrome P-450 monooxygenase …
AV Klotz, JJ Stegeman, C Walsh - Analytical biochemistry, 1984 - Elsevier
A procedure to directly measure the cytochrome P-450-dependent 7-ethoxyresorufin O-deethylase
activity with a visible spectrophotometer is described and compared to the standard …
activity with a visible spectrophotometer is described and compared to the standard …