A distinct human estrogen sulfotransferase (hEST-1) cDNA has been isolated from a human
liver γZap cDNA library using a PCR procedure. The enzymatically active protein has been …

The human cytosolic sulfotransferases (STs), dehydroepiandrosterone sulfotransferase (DHEA-ST)
and the phenol-sulfating form of phenol sulfotransferase, (P-PST), have been …

Breast cancers require the presence of estrogens for the maintenance of growth at some time
in the course of their development, as does normal breast tissue. Sulfation is an important …

Aryl- (SULT1A1), estrogen- (SULT1E1), and hydroxysteroid- (SULT2A1) sulfotransferases (SULTs)
are active determinants of xenobiotic detoxication and hormone metabolism in the …

Sulfation is an important conjugation reaction for a wide range of endogenous and exogenous
compounds in humans, including steroids, bile acids, catecholamine neurotransmitters …

The sulphotransferase (SULT) gene family is involved with the conjugation of many small
drugs, xenobiotics and endogenous compounds. In this report, we describe the cloning and …

Estrogen stimulation is an important factor in human breast cancer cell growth and development.
Metabolism of β-estradiol (E 2 ), the major endogenous human estrogen, is important in …

During the secretory phase of the human menstrual cycle, the endometrium is minimally
responsive to the estrogens secreted from the ovaries. Conjugation of beta-estradiol (E2) with …

Raloxifene and 4-hydroxytamoxifen (4-OHT) are important estrogen-related drugs used in
the treatment of osteoporosis and breast cancer. Sulfation is involved in the metabolism and …

Dehydroepiandrosterone sulphotransferase (DHEA-ST) catalyses the 3′-phosphoadenosine
5′-phosphosulphate-dependent sulphation of a wide variety of steroids in human liver …