Alleviating the access abyss in palliative care and pain relief—an imperative of universal health coverage: the Lancet Commission report

…, BD Paudel, M Elsner, JA Gillespie, KJ Hofman… - The Lancet, 2018 - thelancet.com
In agonising, crippling pain from lung cancer, Mr S came to the palliative care service in
Calicut, Kerala, from an adjoining district a couple of hours away by bus. His body language …

Defining and conceptualising the commercial determinants of health

…, A Erzse, N Freudenberg, S Friel, KJ Hofman… - The Lancet, 2023 - thelancet.com
Although commercial entities can contribute positively to health and society there is growing
evidence that the products and practices of some commercial actors—notably the largest …

Towards unified and impactful policies to reduce ultra-processed food consumption and promote healthier eating

…, S Barquera, C Corvalan, KJ Hofman… - The lancet Diabetes & …, 2021 - thelancet.com
The global surges in obesity and nutrition-related non-communicable diseases (NCDs)
have created a need for decisive new food policy initiatives. A major concern has been the …

The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: intestinal absorption properties, biochemical and pharmacodynamic effects

…, E Gyzander, M Elg, T Antonsson, KJ Hoffmann… - Thrombosis research, 2001 - Elsevier
Suboptimal gastrointestinal absorption is a problem for many direct thrombin inhibitors. The
studies presented herein describe the new oral direct thrombin inhibitor H 376/95, a prodrug …

The global burden of chronic diseases: overcoming impediments to prevention and control

D Yach, C Hawkes, CL Gould, KJ Hofman - Jama, 2004 - jamanetwork.com
Chronic diseases are the largest cause of death in the world. In 2002, the leading chronic
diseases—cardiovascular disease, cancer, chronic respiratory disease, and diabetes—caused …

Metabolism of metoprolol‐(3H) in man, the dog and the rat

KO Borg, E Carlsson, KJ Hoffmann… - Acta pharmacologica …, 1975 - Wiley Online Library
The main urinary metabolites of metoprolol‐( 3 H) in man, the dog and the rat were identified
by gas chromatography and mass spectrometry by comparison with synthesized reference …

[HTML][HTML] Evidence that a tax on sugar sweetened beverages reduces the obesity rate: a meta-analysis

…, JL Veerman, SM Tollman, MY Bertram, KJ Hofman - BMC public health, 2013 - Springer
… These include processed food (high in salt, sugar and fat), high energy density food (energy
density refers to the amount of energy in a given weight of food in kcal/g or kJ/g) [13], fast …

Absorption, distribution, metabolism, and excretion of ximelagatran, an oral direct thrombin inhibitor, in rats, dogs, and humans

UG Eriksson, U Bredberg, KJ Hoffmann… - Drug metabolism and …, 2003 - ASPET
The absorption, metabolism, and excretion of the oral direct thrombin inhibitor, ximelagatran,
and its active form, melagatran, were separately investigated in rats, dogs, and healthy …

Implementation science

T Madon, KJ Hofman, L Kupfer, RI Glass - Science, 2007 - science.org
The new initiative provided conditional financial incentives for poor rural families, on the
basis of their use of prenatal, child health, and nutritional services provided by local clinics. …

Identification of the major covalent adduct formed in vitro and in vivo between acetaminophen and mouse liver proteins.

KJ Hoffmann, AJ Streeter, DB Axworthy… - Molecular pharmacology, 1985 - ASPET
Improved analytical methodology has been developed for the structural characterization of
covalently bound drug-protein adducts and has been applied to an investigation of the …