Alleviating the access abyss in palliative care and pain relief—an imperative of universal health coverage: the Lancet Commission report
…, BD Paudel, M Elsner, JA Gillespie, KJ Hofman… - The Lancet, 2018 - thelancet.com
In agonising, crippling pain from lung cancer, Mr S came to the palliative care service in
Calicut, Kerala, from an adjoining district a couple of hours away by bus. His body language …
Calicut, Kerala, from an adjoining district a couple of hours away by bus. His body language …
Defining and conceptualising the commercial determinants of health
Although commercial entities can contribute positively to health and society there is growing
evidence that the products and practices of some commercial actors—notably the largest …
evidence that the products and practices of some commercial actors—notably the largest …
Towards unified and impactful policies to reduce ultra-processed food consumption and promote healthier eating
The global surges in obesity and nutrition-related non-communicable diseases (NCDs)
have created a need for decisive new food policy initiatives. A major concern has been the …
have created a need for decisive new food policy initiatives. A major concern has been the …
The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: intestinal absorption properties, biochemical and pharmacodynamic effects
…, E Gyzander, M Elg, T Antonsson, KJ Hoffmann… - Thrombosis research, 2001 - Elsevier
Suboptimal gastrointestinal absorption is a problem for many direct thrombin inhibitors. The
studies presented herein describe the new oral direct thrombin inhibitor H 376/95, a prodrug …
studies presented herein describe the new oral direct thrombin inhibitor H 376/95, a prodrug …
The global burden of chronic diseases: overcoming impediments to prevention and control
Chronic diseases are the largest cause of death in the world. In 2002, the leading chronic
diseases—cardiovascular disease, cancer, chronic respiratory disease, and diabetes—caused …
diseases—cardiovascular disease, cancer, chronic respiratory disease, and diabetes—caused …
Metabolism of metoprolol‐(3H) in man, the dog and the rat
KO Borg, E Carlsson, KJ Hoffmann… - Acta pharmacologica …, 1975 - Wiley Online Library
The main urinary metabolites of metoprolol‐( 3 H) in man, the dog and the rat were identified
by gas chromatography and mass spectrometry by comparison with synthesized reference …
by gas chromatography and mass spectrometry by comparison with synthesized reference …
[HTML][HTML] Evidence that a tax on sugar sweetened beverages reduces the obesity rate: a meta-analysis
… These include processed food (high in salt, sugar and fat), high energy density food (energy
density refers to the amount of energy in a given weight of food in kcal/g or kJ/g) [13], fast …
density refers to the amount of energy in a given weight of food in kcal/g or kJ/g) [13], fast …
Absorption, distribution, metabolism, and excretion of ximelagatran, an oral direct thrombin inhibitor, in rats, dogs, and humans
UG Eriksson, U Bredberg, KJ Hoffmann… - Drug metabolism and …, 2003 - ASPET
The absorption, metabolism, and excretion of the oral direct thrombin inhibitor, ximelagatran,
and its active form, melagatran, were separately investigated in rats, dogs, and healthy …
and its active form, melagatran, were separately investigated in rats, dogs, and healthy …
Implementation science
The new initiative provided conditional financial incentives for poor rural families, on the
basis of their use of prenatal, child health, and nutritional services provided by local clinics. …
basis of their use of prenatal, child health, and nutritional services provided by local clinics. …
Identification of the major covalent adduct formed in vitro and in vivo between acetaminophen and mouse liver proteins.
KJ Hoffmann, AJ Streeter, DB Axworthy… - Molecular pharmacology, 1985 - ASPET
Improved analytical methodology has been developed for the structural characterization of
covalently bound drug-protein adducts and has been applied to an investigation of the …
covalently bound drug-protein adducts and has been applied to an investigation of the …