Oligomeric forms of amyloid-β peptide (Aβ) are thought to play a pivotal role in the
pathogenesis of Alzheimer's disease (AD), but the mechanism involved is still unclear. Here, we …

Fukuyama-type congenital muscular dystrophy (FCMD), one of the most common autosomal
recessive disorders in Japan (incidence is 0.7–1.2 per 10,000 births), is characterized by …

Muscle-eye-brain disease (MEB) is an autosomal recessive disorder characterized by
congenital muscular dystrophy, ocular abnormalities, and lissencephaly. Mammalian O-mannosyl …

In this study, we propose a speaker-dependent WaveNet vocoder, a method of synthesizing
speech waveforms with WaveNet, by utilizing acoustic features from existing vocoder as …

Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal lining of the upper
aerodigestive tract. Tobacco and alcohol use have been reported to be associated with …

Spinocerebellar ataxia type 31 (SCA31) is an adult-onset autosomal-dominant neurodegenerative
disorder showing progressive cerebellar ataxia mainly affecting Purkinje cells. The …

Exquisitely precise synapse formation is crucial for the mammalian CNS to function correctly.
Retinal photoreceptors transfer information to bipolar and horizontal cells at a specialized …

Glycosylation is an essential post-translational modification that underlies many biological
processes and diseases. α-dystroglycan (α-DG) is a receptor for matrix and synaptic proteins …

Fukuyama muscular dystrophy (FCMD; MIM253800), one of the most common autosomal
recessive disorders in Japan, was the first human disease found to result from ancestral …

We studied 20 single nucleotide polymorphisms in 18 candidate genes for association with
Parkinson's disease. We found that homozygosity for the V66M polymorphism of the brain‐…