The purpose of the present study was to investigate the effects of particle size on the dissolution
and oral absorption of cilostazol. Three types of suspensions having different particle …

The aim of this study was to establish a new preparation method for solid dispersion formulation
(SDF) of tacrolimus, a poorly water-soluble drug, without dichloromethane, because no …

The relationship between the time-dependent change in serum proteins adsorbed on
nanoparticles and their disposition to the liver was investigated by employing lecithin-coated …

We evaluated the in vivo disposition characteristics of polystyrene nanospheres (NS) with
the particle size of 50 nm (NS-50) pre-coated with human serum albumin (HSA) after …

To develop the suitable film formulations of propranolol hydrochloride (PPL) containing
enhancers for transdermal use, polymeric film formulations were prepared by employing ethyl …

The gastrointestinal (GI) absorption of orally administered drugs is determined by not only
the permeability of GI mucosa but also the transit rate in the GI tract. It is well known that the …

The objective of this study is to evaluate the biodistribution characteristics of liposomes
surface-modified with the mixture of polyethylene glycol (PEG) and polyvinyl alcohol (PVA) as a …

To find out potent paclitaxel (PTX) formulations for cancer chemotherapy, we formulated
PTX in O/W emulsion and liposome selected as candidates of nanocarriers for PTX. Surface …

The in vivo disposition of polystyrene microsphere (MS) with the particle size of 50 nm (MS-50)
or 500 nm (MS-500) was characterized after intravenous administration to rats. A rapid …

We evaluated the in vivo anti-tumor effect of polyethylene glycol-modified liposomal
doxorubicin (PEG liposomal DOX) in the DOX-resistant Colon-26 cancer cells (C26/DOX)-bearing …