Effects of olopatadine, a new antiallergic agent, on human liver microsomal cytochrome P450 activities

J Kajita, K Inano, E Fuse, T Kuwabara… - Drug metabolism and …, 2002 - ASPET
Olopatadine, a new histamine H 1 receptor-selective antagonist, is a tricyclic drug containing
an alkylamino moiety. Some compounds containing a similar alkylamino group form a …

Reasons for reduced activities of 17α-hydroxylase and C17-C20 lyase in spite of increased contents of cytochrome P-450 in mature rat testis fetally irradiated with …

I Hiroshi, IO Hiroko, S Keiko, I Kiyomi - Journal of steroid biochemistry, 1990 - Elsevier
Pregnant rats received whole body irradiation with 2.6 Gy gamma-ray from a 60 Co source
at Day 20 of gestation. When pups were 4 months old, activities of electron transport system …

Susceptibility of fetal, virgin, pregnant and lactating rats for the induction of mammary tumors by gamma rays

H Inano, K Suzuki, M Onoda… - Radiation …, 1996 - meridian.allenpress.com
Pregnant Wistar-MS rats received a whole-body irradiation of 0-2.6 Gy γ rays at day 20 of
pregnancy. The mother rats were implanted with a diethylstilbestrol (DES) pellet 30 days after …

Ketoconazole as a possible universal inhibitor of cytochrome P-450 dependent enzymes: its mode of inhibition

Y HIGASHI, M OMURA, K SUZUKI, H INANO… - Endocrinologia …, 1987 - jstage.jst.go.jp
Modes of inhibition and binding of ketoconazole, an orally antimycotic agent, to NADPH-cytochrome
P-450dependent enzymes were investigated using subcellular fractions of human …

Mammary tumorigenesis by radiation and its prevention

M Onoda, K Suzuki, H Inano - Hoshasen Kagaku, 1999 - osti.gov
Since the breast cancer in women emerged as an important risk associated with exposure to
ionizing radiation, we have investigated to clarify the relationship between the induction of …

Biological Activities of 7±-Hydroxylated C19-Steroids and Changes in Rat Testicular 7±-Hydroxylase Activity with Gonadal Status

H INANO, K SUZUKI, K WAKABAYASHI… - …, 1973 - academic.oup.com
Activity of the steroid 7±-hydroxylase which converts androstenedione into 7±-hydroxyandrostenedione
was detected in testicular microsomal fraction of adult rats, but no significant …

Inhibitory effects of WR-2721 and cysteamine on tumor initiation in mammary glands of pregnant rats by radiation

H Inano, M Onoda, K Suzuki… - Radiation …, 2000 - meridian.allenpress.com
Inano, H., Onoda, M., Suzuki, K., Kobayashi, H. and Wakabayashi, K. Inhibitory Effects of WR-2721
and Cysteamine on Tumor Initiation in Mammary Glands of Pregnant Rats by …

Steroid Hormone Production in Testis, Ovary, and Adrenal Gland of Immature Rats Irradiated in Utero with 60Co

H Inano, K Suzuki, H Ishii-Ohba, Y Imada… - Radiation …, 1989 - meridian.allenpress.com
Pregnant rats received whole-body irradiation at 20 days of gestation with 2.6 Gy γ rays from
a 60 Co source. Endocrinological effects before maturation were studied using testes and …

Radiation-induced mammary tumorigenesis in pseudopregnant rats mated with vasectomized partners

H Inano, K Suzuki - Cancer letters, 1997 - Elsevier
Pseudopregnancy was induced in Wistar-MS female rats by mating with male rats 1 month
after vasectomy. Pseudopregnant rats received whole-body irradiation with 2.6 Gy γ-rays at …

Identification of 7α-hydroxylated androgens as the metabolites of androstenedione by testicular microsomal fraction of rats

H Inano, K Tsuno, B Tamaoki - Biochemistry, 1970 - ACS Publications
… of rat testicular glands (Inano et al., 1970). When enzyme kinetic studies of the 17/3-hydroxysteroid
dehydrogenase in the state of the testicular microsomes were carried out in the presence of …