= Ph), when hydrolyzed under the above conditions, afforded a quantitative yield of (25)-azidophenylacetic
acid (6d)(R= Ph) having a minimum enantiomeric purity of 99.5%. In the most …

Purpose: Prostate cancer eventually recurs during androgen deprivation therapy despite
castrate levels of serum androgens. Expression of androgen receptor and androgen receptor–…

A cDNA encoding a human cytochrome P450 arachidonic acid epoxygenase was isolated
from a human liver cDNA library. Sequence analysis revealed that this 1,876-base pair cDNA …

The determination of salivary biomarkers as a means of monitoring general health and for
the early diagnosis of disease is of increasing interest in clinical research. Based on the …

Epoxyeicosatrienoic acids (EETs) generated from arachidonic acid by cytochrome P450 (CYP)
epoxygenases have beneficial effects in certain cardiovascular and kidney diseases. …

An analytical approach is reported for the characterization of the specific glycans found on
highly glycosylated proteins based on a combination of specific proteolysis and …

A long-standing problem inthe identification and structure proof of fatty acids and similar
compounds has been the deter-mination of the position of the double bond. The positive ion …

A cDNA encoding a P450 monooxygenase was amplified from reverse transcribed rat heart
and liver total RNA by polymerase chain reaction using primers based on the 5′- and 3′-…

The androgen receptor (AR) mediates the growth of benign and malignant prostate in response
to dihydrotestosterone (DHT). In patients undergoing androgen deprivation therapy for …

Deoxyribose phosphate (dRP) removal by DNA polymerase β (Pol β) is a pivotal step in base
excision repair (BER). To identify BER cofactors, especially those with dRP lyase activity, …