Curcumin (diferuloylmethane), a yellow pigment that is obtained from the rhizomes of Curcuma
longa Linn., is a major component of turmeric and is commonly used as a spice and food-…

In this study, we investigated the effects of the major green tea polyphenol, (-)-epigallocatechin-3-gallate
(EGCG), on high-fat–induced obesity, symptoms of the metabolic syndrome, …

The tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) has been studied for chronic disease
preventive effects, and is marketed as part of many dietary supplements. However, case-…

In a previous study (ZY Wang et al., Cancer Res., 52: 1162–1170, 1992), we found that
administration of a water extract of green tea leaves as the sole source of drinking fluid inhibited …

To gain insight into melanoma pathogenesis, we characterized an insertional mouse mutant,
TG3, that is predisposed to develop multiple melanomas 1 , 2 . Physical mapping identified …

Autism symptoms, including impairments in language development, social interactions, and
motor skills, have been difficult to model in rodents. Since children exposed in utero to …

The aim of this study was to investigate the effects of (−)-epigallocatechin-3-gallate (EGCG)
on newly developed high-fat/Western-style diet-induced obesity and symptoms of metabolic …

The effect of po administration of tea on nitrosamine-induced carcinogenesis was investigated.
Female A/J mice were given N-nitrosodiethylamine (NDEA) (10 mg/kg) po once a week …

Development of cancer cell resistance, low accumulation of therapeutic drug in the lungs,
and severe adverse treatment side effects represent main obstacles to efficient chemotherapy …

The present study investigated the inhibitory effects of Polyphenon E [a standardized green
tea polyphenol preparation containing 65% (−)-epigallocatechin-3-gallate] and caffeine on 4-…