A recent study, identifying several sulfate conjugates, appears to have led to a full qualitative
account of propranolol metabolism in man. The objective of the present investigation was to …

The patency rate of internal mammary artery grafts is reported to be better than that of
saphenous vein grafts in myocardial revascularization operations. To identify a possible …

Numerous studies have been carried out on drug‐polymer sustained release systems designed
for implantation. The majority of these efforts have been directed toward determining the …

The metabolic chiral inversion of R-(-)-ibuprofen has been stud-led in human subjects by
means of specific deutenum labeling and stereoselective gas chromatography-mass …

… 410 Olanoff et al. … 412 Olanoff et al. … Walle T, Walle UK, Olanoff LS. Quantitative
account of propranolol metabolism in urine of normal man. Drug Metab Dispos 1985;13:204-9. …

The buccal absorption of flurbiprofen was studied in normal men to quantify the transport
from the oral cavity in humans and to evaluate the closed—perfusion cell apparatus as a …

Our aim was to determine possible stereoselectivity in the plasma binding of propranolol.
Equilibrium dialysis with plasma from seven healthy subjects and a deuterium‐labeled …

Certain types of hydroxypropyl methylcellulose ethers, when admixed with a therapeutic
agent and compressed into a solid dosage form, are found to display a bimodal drug release …

Our objective was to determine the kinetics of (+)‐ and (–)‐propranolol after intravenous
doses of racemic drug. Five normal subjects received 0.1 mg/kg of a pseudoracemate of …

A controlled tetracycline delivery device, consisting of a membrane enclosed trilaminate
disc fabricated from a series of 2-hydroxyethylmethacrylate/methylmethacrylate copolymers, …