[HTML][HTML] Vitamin D and respiratory tract infections: a systematic review and meta-analysis of randomized controlled trials

P Bergman, ÅU Lindh, L Björkhem-Bergman, JD Lindh - PloS one, 2013 - journals.plos.org
Background Low levels of 25-OH vitamin D are associated with respiratory tract infection (RTI).
However, results from randomized controlled trials are inconclusive. Therefore, we …

Vitamin D3 supplementation in patients with frequent respiratory tract infections: a randomised and double-blind intervention study

…, RS Rekha, B Agerberth, L Björkhem-Bergman… - BMJ open, 2012 - bmjopen.bmj.com
Background Low serum levels of 25-hydroxyvitamin D 3 are associated with an increased
risk of respiratory tract infections (RTIs). Clinical trials with vitamin D 3 against various …

[HTML][HTML] The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone: a novel mechanism for defense against oxidative stress

…, A Damdimopoulos, L Björkhem-Bergman… - Journal of Biological …, 2003 - ASBMB
The selenoprotein thioredoxin reductase (TrxR1) is an essential antioxidant enzyme known
to reduce many compounds in addition to thioredoxin, its principle protein substrate. Here …

[HTML][HTML] What is a relevant statin concentration in cell experiments claiming pleiotropic effects?

L Björkhem-Bergman, JD Lindh… - British journal of clinical …, 2011 - ncbi.nlm.nih.gov
Apart from their lipid-lowering effects statins have been ascribed a number of other functions
including antiinflammatory and immunomodulatory properties [1]. Notably, most available …

Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age

…, S Aleman, L Björkhem-Bergman… - Proceedings of the …, 2023 - National Acad Sciences
Pre-existing SARS-CoV-2-reactive T cells have been identified in SARS-CoV-2-unexposed
individuals, potentially modulating COVID-19 and vaccination outcomes. Here, we provide …

[HTML][HTML] Vitamin D in pain management

M Helde-Frankling, L Björkhem-Bergman - International journal of …, 2017 - mdpi.com
Vitamin D is a hormone synthesized in the skin in the presence of sunlight. Like other
hormones, vitamin D plays a role in a wide range of processes in the body. Here we review the …

Interface management of pharmacotherapy. Joint hospital and primary care drug recommendations

L Björkhem-Bergman, E Andersén-Karlsson… - European journal of …, 2013 - Springer
Purpose In September 2012 an interactive course on the “Interface Management of
Pharmacotherapy” was organized by the Stockholm Drug and Therapeutics Committee in …

Comparison of endogenous 4β-hydroxycholesterol with midazolam as markers for CYP3A4 induction by rifampicin

L Björkhem-Bergman, T Bäckström, H Nylén… - Drug Metabolism and …, 2013 - ASPET
CYP3A4, considered the most important enzyme in drug metabolism, is often involved in
drug-drug interactions. When developing new drugs, appropriate markers for detecting …

[HTML][HTML] Studies on the Antibacterial Effects of Statins - In Vitro and In Vivo

…, J Andersson, L Björkhem-Bergman - PloS one, 2011 - journals.plos.org
Background Statin treatment has been associated with a beneficial outcome on respiratory
tract infections. In addition, previous in vitro and in vivo experiments have indicated favorable …

[HTML][HTML] Antibiotic treatment in end-of-life cancer patients—a retrospective observational study at a palliative care center in Sweden

…, J Bergqvist, P Bergman, L Björkhem-Bergman - Cancers, 2016 - mdpi.com
Background: The aim of this study was to elucidate whether palliative cancer patients benefit
from antibiotic treatment in the last two weeks of life when an infection is suspected. Method…