In our study, we tested the hypothesis whether valproic acid (VPA) in therapeutic concentrations
has potential to affect expression of CYP3A4 and MDR1 via constitutive androstane …

CYP3A4 is the most important drug-metabolizing enzyme that is involved in biotransformation
of more than 50% of drugs. Pregnane X receptor (PXR) dominantly controls CYP3A4 …

SP600125, a specific inhibitor of c-Jun-N-Terminal kinase (JNK), was reported as a ligand
and antagonist of aryl hydrocarbon receptor (AhR) [Joiakim A, Mathieu PA, Palermo C, …

Azole antifungal drug ketoconazole has recently been demonstrated as an inhibitor of a
ligand-induced pregnane X receptor (PXR)-mediated transcriptional regulation of the CYP3A4 …

Warfarin is a well-known anticoagulant agent that occurs in two enantiomers, (R)-(+)-warfarin
and (S)-(−)-warfarin. A new liquid chromatography method for the determination of both …

This article describes possibilities of using electromyography (EMG) as an objective method
for identification of wrong muscles work during aimed shooting focused on disciplines of …

The article describes using electromyography as an objective method for identification of
wrong muscles work during aimed shooting focused on sport shooting, especially standing …

This paper is focused on the stability and reliability of interconnections in smart textiles
between textile ribbons and other smart textiles functional blocks. There was selected one …

Wellington County represents a region with an extensive and well developed horse industry.
As a result there is significant potential for development in its rural areas. This study reveals …

The paper discusses the topic of volunteering. A key role in managing volunteer work is to
stimulate them to support internal motivation. The management of volunteers needs to know …