Use of saliva in therapeutic drug monitoring.

MG Horning, L Brown, J Nowlin… - Clinical …, 1977 - academic.oup.com
We measured the concentrations of phenobarbital, phenytoin, primidone, ethosuximide,
antipyrine, and caffeine in paired samples of saliva and plasma by gas chromatograph-mass …

Infants exposed in utero to antiepileptic drugs: a prospective study

RM Hill, WM Verniaud, MG Horning… - American Journal of …, 1974 - jamanetwork.com
Twenty-eight newly born infants exposed in utero to various anticonvulsant drugs have been
followed up from birth to 36 months of age, and their clinical status has been compared to …

Depot fat as source of increased liver triglycerides after ethanol.

MG Horning, EA Williams, HM Maling, BB Brodie… - 1960 - cabidigitallibrary.org
Rats given 4.8 g ethanol per kg bodyweight as a 50% solution had after 18 h 24.1 mg
triglycerides per g liver compared with 6.9 for untreated rats; linoleic acid contents were 6.1 and …

Congenital lipoid adrenal hyperplasia in an eight-year-old phenotypic female

…, CM JOHNSON, MG HORNING… - The Journal of …, 1973 - academic.oup.com
Congenital lipoid adrenal hyperplasia (CLAH) was described as an invariably fatal disease
in infancy manifested by severe adrenal insufficiency with lack of differentiation of the …

The study of urinary acids and related compounds by gas phase analytical methods

MG Horning, EA Boucher… - Journal of …, 1967 - academic.oup.com
A general method has been developed for the analysis of urinary acids by gas chromatography
using the methyl ester-trimethylsilyl ether (ME-TMSi) derivatives in a temperature …

Elimination of antipyrine and benzo [a] pyrene metabolism in cultured human lymphocytes

…, M Luyten‐Kellermann, MG Horning… - Clinical …, 1976 - Wiley Online Library
A strong correlation was found in a carefully selected homogenous population (n = 57) between
antipyrine plasma half‐life and the percent induction of aryl hydrocarbon hydroxylase by …

A rapid procedure for the isolation of drugs and drug metabolites from plasma

MG Horning, EA Boucher, M Stafford, EC Horning - Clinica Chimica Acta, 1972 - Elsevier
A rapid procedure for the extraction of neutral and basic drugs and drug metabolites with
isopropanol from diluted plasma saturated with potassium carbonate has been developed. The …

Clinical applications of gas chromatograph/mass spectrometer/computer systems

MG Horning, J Nowlin, CM Butler… - Clinical …, 1975 - academic.oup.com
Gas chromatograph/mass spectrometer/computer systems can be used to quantify a wide
variety of compounds of clinical interest. A quadrupole instrument operated in the chemical …

Correlation of aryl hydrocarbon hydroxylase activity of human lymphocyte cultures and plasma elimination rates for antipyrine and phenylbutazone

…, M LUYTEN-KELLERMANN, MG HORNING… - Drug Metabolism and …, 1975 - ASPET
A high correlation was observed between the aryl hydrocarbon hydroxylase activities in
short-term lymphocyte cultures of 23 individuals and their plasma half-lives of antipyrine and …

Enzymatic degradation of the cholesterol side chain in cell-free preparations

CB Anfinsen, MG Horning - Journal of the American Chemical …, 1953 - ACS Publications
OT-Cyanoacetophenone 95 237 C^ HiaNg1 69.28 69.47 4.74 5.0 3 All yields of crude material.
6 Recrystallized from pyridine and therefore tabulated data are those for the hydrazone …