Synthetic analogs of curcumin modulate the function of multidrug resistance–linked ATP-binding cassette transporter ABCG2
M Murakami, S Ohnuma, M Fukuda, EE Chufan… - Drug Metabolism and …, 2017 - ASPET
Multidrug resistance (MDR) caused by the overexpression of ATP-binding cassette (ABC)
transporters in cancer cells is a major obstacle in cancer chemotherapy. Previous studies have …
transporters in cancer cells is a major obstacle in cancer chemotherapy. Previous studies have …
Reversibility of the thia-Michael reaction of cytotoxic C 5-curcuminoid and structure–activity relationship of bis-thiol-adducts thereof
A Kohyama, M Fukuda, S Sugiyama… - Organic & …, 2016 - pubs.rsc.org
C5-curcuminoids [aka bis(arylmethylidene)acetones] are curcumin analogues bearing a
reactive cross-conjugated dienone structure essential for eliciting cytotoxicity. To gain insight …
reactive cross-conjugated dienone structure essential for eliciting cytotoxicity. To gain insight …
Study on decrease of reservoir permeability due to deposition of silica dissolved in reinjection water
R Itoi, H Maekawa, M Fukuda, K Jinno… - journal of the …, 1986 - jstage.jst.go.jp
The decrease of permeablity caused by the deposition of silica in a porous column(50 cm•~
5 cm ƒÓ) has been studied using the Otake geothermal water at about 90• Ž and at pH 8. A …
5 cm ƒÓ) has been studied using the Otake geothermal water at about 90• Ž and at pH 8. A …
EXPERIMENTAL STUDY ON THE SILICA DEPOSITION IN A POROUS MEDIUM.
R Itoi, H Maekawa, M Fukuda… - Transactions …, 1984 - kyushu-u.elsevierpure.com
The decrease in permeability of a porous column (50 cm long and 5 cm in diameter) in a
cylinder due to the deposition of silica scale has been examined. The temperature of the Otake …
cylinder due to the deposition of silica scale has been examined. The temperature of the Otake …
Design, Synthesis, and Biological Evaluation of Water-Soluble Prodrugs of C5-Curcuminoid GO-Y030 Based on Reversible Thia-Michael Reaction
H Yamakoshi, M Fukuda, H Ikeda, S Fujiki… - Chemical and …, 2024 - jstage.jst.go.jp
… Hiroyuki Yamakoshi , Michihiro Fukuda, Hiro Ikeda, Shogo Fujiki, Aki Kohyama, Shota
Nagasawa, Hanae Shinozaki, Hiroyuki Shibata, Yoshiharu Iwabuchi … 19) Kohyama A …
Nagasawa, Hanae Shinozaki, Hiroyuki Shibata, Yoshiharu Iwabuchi … 19) Kohyama A …
Decrease in reservoir permeability due to deposition of silica dissolved in geothermal injection water numerical simulation in one dimensional flow system
R Itoi, M Fukuda, K JINNO, T Yokoyama… - journal of the …, 1987 - jstage.jst.go.jp
A mathematical model which simulates the previously reported experimental results on
permeability decrease of porous media is proposed. In the model, the silica deposition rate is …
permeability decrease of porous media is proposed. In the model, the silica deposition rate is …
[PDF][PDF] Numerical modeling study of Sibayak geothermal reservoir, North Sumatra, Indonesia
JP Atmojo, R Itoi, M Fukuda, T Tanaka… - Proc. Twenty-Sixth …, 2001 - pangea.stanford.edu
A three-dimensional numerical model of porous type for the Sibayak reservoir is developed
which covers an area of 8 x 8 km2 and a depth 2500 m below sea level. In natural state …
which covers an area of 8 x 8 km2 and a depth 2500 m below sea level. In natural state …
MATHEMATICAL MODEL OF SILICA DEPOSITION IN A POROUS MEDIUM.
…, H Maekawa, K Tatsuta, M Fukuda… - Transactions …, 1985 - kyushu-u.elsevierpure.com
A mathematical model of silica deposition in a porous medium is presented. It consists of
equations of fluid flow, silica concentration and silica deposition. In the model, the effects of …
equations of fluid flow, silica concentration and silica deposition. In the model, the effects of …
[PDF][PDF] An analysis method of tracer tests by using genetic algorithms and its application
…, H Nakamura, R Itoi, M Fukuda - Proc. World Geothermal …, 2000 - geothermal-energy.org
In the case of a tracer test analysis using a nonlinear least squares method, we should notice
that the final estimates are influenced by the initial values of the reservoir properties for the …
that the final estimates are influenced by the initial values of the reservoir properties for the …
Geothermal reservoir simulation for a complex model
M Fukuda, R Itoi, A Koga - Transactions-Geothermal …, 1988 - kyushu-u.elsevierpure.com
Using a complex model consisting of lumped-parameter reservoirs and a fault zone, all
connected by aquifers, a geothermal reservoir simulation was carried out by changing the …
connected by aquifers, a geothermal reservoir simulation was carried out by changing the …