mRNA expression of multiple cytochrome p450 isozymes in four types of cultured skin cells

M Saeki, Y Saito, M Nagano, R Teshima… - International archives of …, 2002 - karger.com
Background: Many drugs are known to induce allergic reactions in the skin. The metabolic
activation of drugs resulting in the formation of protein adducts is thought to be a first step in …

Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide …

…, N Murayama, S Ishida, K Sai, M Nagano… - Drug metabolism and …, 2002 - ASPET
We found nucleotide variability in the 5′-upstream region and exonic sequences of a gene-encoding
canalicular multispecific organic anion transporter/multidrug resistance-…

[HTML][HTML] Biological effects of Mammalian translationally controlled tumor protein (TCTP) on cell death, proliferation, and tumorigenesis

M Nagano-Ito, S Ichikawa - Biochemistry research international, 2012 - hindawi.com
Translationally controlled tumor protein (TCTP) is a highly conserved protein found in
eukaryotes, across animal and plant kingdoms and even in yeast. Mammalian TCTP is …

Functional analysis of three genetic polymorphisms in the glucocorticoid receptor gene

S Koyano, Y Saito, M Nagano, K Maekawa… - … of Pharmacology and …, 2003 - ASPET
Glucocorticoids are widely used as potent anti-inflammatory drugs. Glucocorticoids exert
their pharmacological effects by binding to a glucocorticoid receptor (GR), which promotes …

Substitution of arginine for cysteine 643 of the glucocorticoid receptor reduces its steroid-binding affinity and transcriptional activity

M Nagano, T Nakamura, S Niimi, T Fujino, T Nishimura… - Cancer letters, 2002 - Elsevier
To investigate the mechanism for glucocorticoid resistance in leukemic cells, we sequenced
the coding region of glucocorticoid receptor (GR) gene in ten Japanese leukemic cells. We …

[HTML][HTML] Functional cloning of genes that suppress oxidative stress-induced cell death: TCTP prevents hydrogen peroxide-induced cell death

M Nagano-Ito, A Banba, S Ichikawa - FEBS letters, 2009 - Elsevier
We used retroviral-mediated expression cloning to identify cDNAs that inhibit cell death
induced by oxidative stress. To isolate the genes, we introduced a murine embryonic retroviral …

Allele-specific long-range PCR/sequencing method for allelic assignment of multiple single nucleotide polymorphisms

M Nagano, T Nakamura, S Ozawa, K Maekawa… - Journal of biochemical …, 2003 - Elsevier
We report an allele-specific sequencing method using allele-specific long-range polymerase
chain reaction (PCR) to determine if multiple (specifically, more than three) single …

Maternal program of apoptosis activated shortly after midblastula transition by overexpression of S-adenosylmethionine decarboxylase in Xenopus early embryos

…, C Kaito, Y Yasuhiko, E Kajita, M Nagano… - … and Physiology Part B …, 2000 - Elsevier
When we studied polyamine metabolism in Xenopus embryos, we cloned the cDNA for
XenopusS-adenosylmethionine decarboxylase (SAMDC), which converts SAM (S-…

Cloning ofXenopusTFIIS and Its Expression in Oocytes and Early Embryos

…, J Shinga, M Imagawa, K Arae, M Nagano… - Biochemical and …, 1996 - Elsevier
The transcriptional factor TFIIS has been cloned fromXenopus laevis.The length of the
cDNA is 1668bp and contains the complete open reading frame of 303 amino acids.…

Identification and characterization of a novel alternative splice variant of mouse GMx33α/GPP34

M Nagano-Ito, S Yoshikawa, M Tamura, M Tsurumaki… - Gene, 2007 - Elsevier
We have cloned and characterized a novel splice variant of mouse GMx33α/Golgi-associated
protein of 34 kDa (GPP34), hereby designated GMx33αV/GPP34V. This splice variant …