The lack of information concerning individual variation in drug-metabolizing enzymes is one
of the most important obstacles for designing personalized medicine approaches for …

Four new compounds, oliganthins A–D (1–4), and one known caged xanthone gaudichaudione
H (5) were isolated from the stems of Garcinia oligantha. The structures of the new …

Human cytochrome P450 oxidoreductase (POR) provides electrons for all microsomal
cytochromes P450 (P450s) and plays an indispensable role in drug metabolism catalyzed by this …

The Qiupu River Bridge is the first suspension bridge with the application of a novel anchorage
of root pile foundation. The static behaviors of the bridge were studied in this paper. …

INTRODUCTION The unfolded protein response (UPR) maintains homeostasis of the
endoplasmic reticulum (ER) through a variety of mechanisms, including ER-associated …

How genotypic variation results in phenotypic differences is still a challenge for biology. In
the field of drug metabolism, the means by which specific cytochrome P4502D6 (CYP2D6) …

Stretchable electronics incorporating critical sensing, data transmission, display and powering
functionalities, is crucial to emerging wearable healthcare applications. To date, methods …

Simple and rapid Young's modulus measurements of soft materials adaptable to various
scenarios are of general significance, and they require miniaturized measurement platforms …

Alterations in cardiac G protein-mediated signaling, most prominently G q/11 signaling, are
centrally involved in hypertrophy and heart failure development. Several RGS proteins that …

The lifetime and safety of lithium metal batteries (LMBs) with commercial polyolefin separators
and liquid electrolytes are deteriorated by the lithium dendrites, as well as leakage and …