Ischemia–reperfusion–induced lung injury
… Mingyao Liu … Mingyao Liu … Fischer S, Maclean AA, Liu M, Cardella JA, Slutsky AS, Suga
M, Moreira JF, Keshavjee S. Dynamic changes in apoptotic and necrotic cell death correlate with …
M, Moreira JF, Keshavjee S. Dynamic changes in apoptotic and necrotic cell death correlate with …
Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome
…, M de Perrot, S Fischer, V Edwards, E Cutz, M Liu… - Jama, 2003 - jamanetwork.com
ContextRecent clinical trials have demonstrated a decrease in multiple organ dysfunction
syndrome (MODS) and mortality in patients with acute respiratory distress syndrome (ARDS) …
syndrome (MODS) and mortality in patients with acute respiratory distress syndrome (ARDS) …
Heritable gene targeting in the mouse and rat using a CRISPR-Cas system
…, M Liu, Y Li, N Gao, L Wang, X Lu, Y Zhao, M Liu - Nature …, 2013 - nature.com
To the Editor: CRISPR-Cas systems have been developed as an efficient gene editing
technology in cells and model organisms. Here we use a CRISPR-Cas system to induce genomic …
technology in cells and model organisms. Here we use a CRISPR-Cas system to induce genomic …
Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression
…, Y Zhu, Y Yu, F Liu, K Dong, J Mariscal, Y Liu… - Nature cell …, 2021 - nature.com
Prostate cancer shows remarkable clinical heterogeneity, which manifests in spatial and
clonal genomic diversity. By contrast, the transcriptomic heterogeneity of prostate tumours is …
clonal genomic diversity. By contrast, the transcriptomic heterogeneity of prostate tumours is …
Calcium-calmodulin modulation of the olfactory cyclic nucleotide-gated cation channel
Although several ion channels have been reported to be directly modulated by calcium-calmodulin,
they have not been conclusively shown to bind calmodulin, nor are the modulatory …
they have not been conclusively shown to bind calmodulin, nor are the modulatory …
[HTML][HTML] Normothermic ex vivo lung perfusion in clinical lung transplantation
Background More than 80% of donor lungs are potentially injured and therefore not considered
suitable for transplantation. With the use of normothermic ex vivo lung perfusion (EVLP), …
suitable for transplantation. With the use of normothermic ex vivo lung perfusion (EVLP), …
Technique for prolonged normothermic ex vivo lung perfusion
BACKGROUND: The inhibition of cellular metabolism induced by hypothermia obviates the
possibility of substantial reparative processes occurring during organ preservation. The aim …
possibility of substantial reparative processes occurring during organ preservation. The aim …
[HTML][HTML] Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL
Recently, chimeric antigen receptor (CAR)-T cell therapy has shown great promise in treating
haematological malignancies 1 , 2 , 3 , 4 , 5 , 6 – 7 . However, CAR-T cell therapy currently …
haematological malignancies 1 , 2 , 3 , 4 , 5 , 6 – 7 . However, CAR-T cell therapy currently …
[HTML][HTML] Directional sensing requires Gβγ-mediated PAK1 and PIXα-dependent activation of Cdc42
Efficient chemotaxis requires directional sensing and cell polarization. We describe a
signaling mechanism involving Gβγ, PAK-associated guanine nucleotide exchange factor (PIXα), …
signaling mechanism involving Gβγ, PAK-associated guanine nucleotide exchange factor (PIXα), …
Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways
… Aggarwal, Mingyao Liu; Thymoquinone inhibits tumor angiogenesis and tumor growth
through suppressing AKT and extracellular signal-regulated kinase signaling pathways. Mol …
through suppressing AKT and extracellular signal-regulated kinase signaling pathways. Mol …