… Myung Hee Park Myung Hee Park … Furthermore, alanine substitution of any residue of the
four HE motifs completely abolished DOHH activity (YS Kim and MH Park, unpublished results)…

The unusual basic amino acid, hypusine [N ε -(4-amino-2-hydroxybutyl)-lysine], is a modified
lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. This …

The amino acid, hypusine [N"-(4-amino-2-hydroxybutyl) lysine], a unique component of one
cellular protein, eukaryotic translation initiation factor 5A (eIF-5A, old terminology eIF-4D), is …

When normal human peripheral lymphocytes are treated with mitogen and grown in the
presence of [3H]putrescine or [terminal methylenes-3H]spermidine, label is incorporated …

A single protein of Mr 17,000-19,000 and pI approximately equal to 5.1, found in all animal
cells we have studied to date, undergoes post-translational modification in growing cells to …

The polyamines, putrescine, spermidine, and spermine, are essential polycations, intimately
involved in the regulation of cellular proliferation. Although polyamines exert dynamic …

Hypusine [N Ε -(4-amino-2-hydroxybutyl)lysine] occurs in all eukaryotes at one residue in a
highly conserved protein, the putative eukaryotic translation initiation factor 5A (eIF-5A, old …

Several types of basic compounds structurally related to spermidine, one of the substrates for
deoxyhypusine synthase, were tested as inhibitors of this enzyme. The results indicate that …

Polyamines, putrescine, spermidine and spermine, are ubiquitous in living cells and are
essential for eukaryotic cell growth. These polycations interact with negatively charged …

Purpose The burden of serving as a caregiver is known to impair quality of life (QOL) and
mental health caregivers of cancer patients. However, few studies focused on the caregivers of …