User profiles for N. H. Schebb

Prof. Dr. Nils Helge Schebb

University of Wuppertal
Verified email at uni-wuppertal.de
Cited by 5194

[HTML][HTML] Formation, signaling and occurrence of specialized pro-resolving lipid mediators—what is the evidence so far?

NH Schebb, H Kühn, AS Kahnt, KM Rund… - Frontiers in …, 2022 - frontiersin.org
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins
usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of …

Targeted metabolomics of the arachidonic acid cascade: current state and challenges of LC–MS analysis of oxylipins

I Willenberg, AI Ostermann, NH Schebb - Analytical and bioanalytical …, 2015 - Springer
Quantification of eicosanoids and oxylipins derived from other polyunsaturated fatty acids in
biological samples is crucial for a better understanding of the biology of these lipid mediators…

[PDF][PDF] Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine

…, C May, N Wilck, A Balogh, AI Ostermann, NH Schebb… - Immunity, 2015 - cell.com
Growing empirical evidence suggests that nutrition and bacterial metabolites might impact the
systemic immune response in the context of disease and autoimmunity. We report that long…

MS-based targeted metabolomics of eicosanoids and other oxylipins: Analytical and inter-individual variabilities

…, AI Ostermann, JW Newman, NH Schebb - Free Radical Biology and …, 2019 - Elsevier
Oxylipins, including the well-known eicosanoids, are potent lipid mediators involved in
numerous physiological and pathological processes. Therefore, their quantitative profiling has …

Triclosan impairs excitation–contraction coupling and Ca2+ dynamics in striated muscle

…, W Feng, GC Barrientos, NH Schebb… - Proceedings of the …, 2012 - National Acad Sciences
Triclosan (TCS), a high-production-volume chemical used as a bactericide in personal care
products, is a priority pollutant of growing concern to human and environmental health. TCS …

Comparison of sample preparation methods for the quantitative analysis of eicosanoids and other oxylipins in plasma by means of LC-MS/MS

AI Ostermann, I Willenberg, NH Schebb - Analytical and bioanalytical …, 2015 - Springer
Oxylipins are potent lipid mediators. For the evaluation of their biological roles, several LC-MS
based methods have been developed. While these methods are similar, the described …

Determining the fatty acid composition in plasma and tissues as fatty acid methyl esters using gas chromatography–a comparison of different derivatization and …

…, M Müller, I Willenberg, NH Schebb - … and Essential Fatty Acids, 2014 - Elsevier
Abstract Analysis of the fatty acid (FA) composition in biological samples is commonly carried
out using gas liquid chromatography (GC) after transesterification to volatile FA methyl …

Investigation of human exposure to triclocarban after showering and preliminary evaluation of its biological effects

NH Schebb, B Inceoglu, KC Ahn… - … science & technology, 2011 - ACS Publications
The antibacterial soap additive triclocarban (TCC) is widely used in personal care products.
TCC has a high environmental persistence. We developed and validated a sensitive online …

Comparison of free serum oxylipin concentrations in hyper-vs. normolipidemic men

…, BD Hammock, A Hahn, NH Schebb - … and Essential Fatty …, 2013 - Elsevier
Oxylipins, the oxidation products of unsaturated fatty acids (FA), are potent endogenous
mediators being involved in the regulation of various biological processes such as inflammation, …

[HTML][HTML] Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their …

VB O'Donnell, NH Schebb, GL Milne… - Nature …, 2023 - nature.com
Specialized pro-resolving mediators (SPM) derived from oxygenation of long chain
polyunsaturated fatty acids (PUFA) were originally described by Serhan and colleagues and have …