IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

PJ Gearhart, ND Johnson, R Douglas, L Hood - Nature, 1981 - nature.com
An amino acid sequence analysis of the N-terminal immunoglobulin heavy and light chain
variable regions (V H and V L ) from 16 hybridoma proteins which bind phosphorylcholine as …

Preclinical and toxicology studies of 1263W94, a potent and selective inhibitor of human cytomegalovirus replication

GW Koszalka, NW Johnson, SS Good… - Antimicrobial agents …, 2002 - Am Soc Microbiol
1263W94 is a novel benzimidazole compound being developed for treatment of human
cytomegalovirus infection. No adverse pharmacological effects were demonstrated in safety …

Defensive regurgitation of allelochemicals derived from host cyanogenesis by eastern tent caterpillars

SC Peterson, ND Johnson, JL LeGuyader - Ecology, 1987 - Wiley Online Library
Eastern tent caterpillars regurgitate a droplet of enteric fluid when attacked by predatory ants.
In laboratory bioassays, the regurgitated fluid of caterpillars fed cyanogenic young foliage …

Report on the international workshop on alternative methods for human and veterinary rabies vaccine testing: state of the science and planning the way forward

…, K Gamoh, R Hill, D Reed, V Doelling, N Johnson… - Biologicals, 2012 - Elsevier
Potency testing of most human and veterinary rabies vaccines requires vaccination of mice
followed by a challenge test using an intracerebral injection of live rabies virus. NICEATM, …

The generation of diversity in phosphorylcholine-binding antibodies

…, ST Crews, R Douglas, G Sorensen, N Johnson… - Advances in …, 1984 - Elsevier
Publisher Summary Antibody heavy and light chains are encoded by more than one gene,
thus anticipating the noncontiguous nature of eukaryotic genes and the DNA rearrangements …

[HTML][HTML] Non-animal replacement methods for human vaccine potency testing: state of the science and future directions

…, Y Horiuchi, D Sesardic, P Stickings, NW Johnson… - Procedia in …, 2011 - Elsevier
NICEATM and ICCVAM convened an international workshop to review the state of the
science of human and veterinary vaccine potency and safety testing methods, and to identify …

Virtual prototyping: Concept to production

AB Garcia, RP Gocke, NP Johnson - Defense System Management …, 1994 - apps.dtic.mil
We undertook this research project to assess the feasibility of using virtual prototypes in the
DOD weapon systems acquisition process. Our goal was to identify and assess the current …

Flavonoid aglycones from Eriodictyon californicum resin and their implications for herbivory and UV screening

ND Johnson - Biochemical Systematics and Ecology, 1983 - Elsevier
The flavones luteolin and chrysoeriol and five methylated derivatives of the flavonone
eriodictyol were identified in the external leaf resin of Eriodictyon californicum. These flavonoids …

Report on the international workshop on alternatives to the murine histamine sensitization test (HIST) for acellular pertussis vaccines: State of the science and the path …

…, A Castiaux, M Halder, W Casey, N Johnson… - Biologicals, 2014 - Elsevier
Regulatory authorities require safety and potency testing prior to the release of each
production lot of acellular pertussis (aP)-containing vaccines. Currently, the murine histamine …

Effects of dietary protein and lupine alkaloids on growth and survivorship ofSpodoptera eridania

ND Johnson, BL Bentley - Journal of Chemical Ecology, 1988 - Springer
Toxic chemicals and nutrients are often positively correlated within and among plants. We
studied how such correlations affect the suitability of plants as food for herbivores by …