The path from β-carotene to carlactone, a strigolactone-like plant hormone

…, P Bigler, S Ghisla, H Bouwmeester, P Beyer… - Science, 2012 - science.org
Strigolactones, phytohormones with diverse signaling activities, have a common structure
consisting of two lactones connected by an enol-ether bridge. Strigolactones derive from …

Long-term administration of L-carnitine to humans: effect on skeletal muscle carnitine content and physical performance

S Wächter, M Vogt, R Kreis, C Boesch, P Bigler… - Clinica Chimica …, 2002 - Elsevier
… , and P max between the three time points investigated. At submaximal intensities, the only
difference to the pretreatment values was a 5% increase in V O 2 at 20% and 40% of P max 2 …

Efficacies of Albendazole Sulfoxide and Albendazole Sulfone against In Vitro-Cultivated Echinococcus multilocularis Metacestodes

K Ingold, P Bigler, W Thormann… - Antimicrobial Agents …, 1999 - Am Soc Microbiol
The metacestode stage of Echinococcus multilocularis is the causative agent of alveolar
echinococcosis (AE), a parasitic disease affecting the liver, with occasional metastasis into other …

DEPTQ: distorsionless enhancement by polarization transfer including the detection of quaternary nuclei

R Burger, P Bigler - Journal of Magnetic Resonance, 1998 - Elsevier
A pulse sequence DEPTQ yielding the signals and multiplicity information for all carbon types
including the signals of quaternary carbons and encompassing all the known advantages …

Observation and identification of metabolites emerging during postmortem decomposition of brain tissue by means of in situ 1H‐magnetic resonance spectroscopy

M Ith, P Bigler, E Scheurer, R Kreis… - … in Medicine: An …, 2002 - Wiley Online Library
Postmortem decomposition of brain tissue was investigated by 1 H‐magnetic resonance
spectroscopy (MRS) in a sheep head model and selected human cases. Aiming at the eventual …

A γ-Glutamyl Peptide Isolated from Onion (Allium cepa L.) by Bioassay-Guided Fractionation Inhibits Resorption Activity of Osteoclasts

…, I Tschudi, M Langos, P Bigler… - Journal of agricultural …, 2005 - ACS Publications
One gram of onion added to the food of rats inhibits significantly (p < 0.05) bone resorption
as assessed by the urinary excretion of tritium released from bone of 9-week-old rats …

Brain development:1H magnetic resonance spectroscopy of rat brain extracts compared with chromatographic methods

R Burri, P Bigler, P Straehl, S Posse, JP Colombo… - Neurochemical …, 1990 - Springer
We compared in vitro 1 H magnetic resonance spectroscopy (MRS) measurements of rat
brain extracts (rats: 2–56 days old) with chromatographic measurements and in a further step …

Analysis of nitro musk compounds and their amino metabolites in liquid sewage sludges using NMR and mass spectrometry

JD Berset, P Bigler, D Herren - Analytical Chemistry, 2000 - ACS Publications
A method using HRGC ion trap MS/MS for measuring simultaneously amino metabolites
and the parent compounds, the nitro musks, an important group of organic fragrance …

Multiplicity editing including quaternary carbons: improved performance for the 13C‐DEPTQ pulse sequence

P Bigler, R Kümmerle, W Bermel - Magnetic Resonance in …, 2007 - Wiley Online Library
An improved version of the DEPTQ experiment yielding the signal and multiplicity
information for all carbon types including the signals of quaternary carbons is proposed. It …

In vitro characterization of Synechocystis CYP120A1 revealed the first nonanimal retinoic acid hydroxylase

A Alder, P Bigler, D Werck‐Reichhart… - The FEBS …, 2009 - Wiley Online Library
Retinoids are C 20 apocarotenoids that have various important functions in metazoans. In
addition, several findings suggest their occurrence in eubacteria, including cyanobacteria. It …