To establish the relationship between ultraviolet‐B radiation and squamous cell carcinoma (SCC),
basal cell carcinoma (BCC), and actinic keratosis (AK), a cross‐sectional prevalence …

Benzo[a]pyrene (B[a]P), a ubiquitous environmental, tobacco and dietary carcinogen, has
been implicated in human cancer etiology. The role of human cytochrome P450 1B1 in the …

Background: Glutathione S-transferases (GSTs) are encoded by a superfamily of genes and
play a role in the detoxification of potential carcinogens. In a nested case-control study, we …

Mounting evidence suggests that catechol metabolites of estradiol may contribute to the
development of estrogen-induced cancers. O-Methylation, catalyzed by catechol-O-…

Human cytochrome P450 (P450) 1B1 (CYP1B1) has recently been shown to be an important
enzyme in the activation of diverse procarcinogens such as arylarenes, nitroarenes, and …

BACKGROUND Advancements in the quality and availability of highly sensitive analytical
instrumentation and methodologies have led to increased interest in the use of microsamples. …

Background The steady worldwide increase in the incidence of non-Hodgkin lymphoma
during the past few decades remains mostly unexplained. Several studies suggest that there …

Cytochromes P450 1A1 and 1B1 are known to bioactivate procarcinogens such as polycyclic
aromatic hydrocarbons (PAHs) found in cigarette smoke and are inducible via an Ah …

Background Individuals with a personal history of nonmelanoma skin cancer (NMSC) may
have an increased risk of subsequent noncutaneous malignancies. To test this hypothesis, we …

A nested case-control study was conducted to examine the association between serum
concentrations of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE), the primary metabolite of 1…