(First of Two Parts) THE prostaglandins and thromboxane A 2 are biologically active
metabolites of arachidonic acid. Their actions and the pharmacologic agents that influence their …

Smoking is a known risk factor for bladder cancer. The product of the GSTM1 gene,
glutathione S-transferase M1 (GSTM1), is involved in the detoxification of polycyclic aromatic …

… -FI56, 1979 Gerkens JF, Branch RA. The influence of sodium … Gerkens JF, Heidemann HTh,
Jackson EK, Branch RA. Ami… GF, Jackson EK, Branch RA. Effect of aminophylline on renal …

… With mephenytoin, the urinary SIR enantiomeric ratio values indicated two discrete populations
… Kiipfer A, Branch RA: Stereoselective mephobarbital hydroxylation cosegregates with …

Background The liver plays a significant role in drug metabolism; thus it would be expected
that liver disease may have a detrimental effect on the activity of cytochrome P450 (CYP) …

… Frye RF, Branch RA. Improved high performance liquid chromatographic determination
of debrisoquine and 4-hydroxydebrisoquine in human urine following direct injection. J …

BACKGROUND: Intrahepatic arterial yttrium 90 ( 90 Y) microspheres have been proposed
as a less toxic, less invasive therapeutic option to transhepatic arterial chemoembolization (…

We investigated prostacyclin (PGI 2 ) biosynthesis during pregnancy by measuring urinary
excretion of 2,3-dinor-6-keto-prostaglandin F 1α (dinor) and 15-keto-13,14-dihydro-2,3-dinor-6…

… Branch, MD … School of Medicine, Nashville, TN 37232 (Dr Branch). … Gerkens JF,
Branch RA: The influence of sodium status and furosemide on canine acute amphotericin B …

Tobacco use is an established cause of bladder cancer. The ability to detoxify aromatic
amines, which are present in tobacco and are potent bladder carcinogens, is compromised in …