Previous studies have suggested a possible pain-modulatory role for histamine H 3 receptors,
but the localization of these receptors and nature of this modulation is not clear. In order to …

J. Neurochem. (2011) 117, 1–18. Abstract The cannabinoid type‐1 (CB 1 ) receptor is a G
protein‐coupled receptor that binds the main active ingredient of marijuana, Δ 9 ‐…

Improgan, a chemical congener of cimetidine, is a highly effective non-opioid analgesic when
injected into the CNS. Despite extensive characterization, neither the improgan receptor, …

Adapt78 (DSCR1/calcipressin/MCIP1) is a potent natural inhibitor of calcineurin, an
important intracellular phosphatase that mediates many cellular responses to calcium. We …

[ 3 H]Cimetidine (3HCIM) specifically binds to an unidentified site in the rat brain. Because
recently described ligands for this site have pharmacological activity, 3HCIM binding was …

[ 3 H]cimetidine, a radiolabeled histamine H 2 receptor antagonist, binds with high affinity to
an unknown hemoprotein in the brain which is not the histamine H 2 receptor. Improgan, a …

The neurotransmitter histamine is inactivated in the CNS by histamine N-methyltransferase (HNMT).
However, HNMT has been localized to the cytosol of neurons and an active uptake …

… and Porten 2003, 352–353), and they were employed in administrative texts that relate to
the respective objects; Aramaic loanwords in Egyptian are few and far between (Stadel 2009, …

The evolution of gravitationally unstable protoplanetary gaseous disks has been studied
with the use of three-dimensional smoothed particle hydrodynamics simulations with …

Tearful crying is a ubiquitous and likely uniquely human phenomenon. Scholars have argued
that emotional tears serve an attachment function: Tears are thought to act as a social glue …