User profiles for Richard A Thompson

Richard A. Thompson

RIA iMed, AstraZeneca
Verified email at comhem.se
Cited by 2321

A review of reaction rates and thermodynamic and transport properties for an 11-species air model for chemical and thermal nonequilibrium calculations to 30000 K

RN Gupta, JM Yos, RA Thompson, KP Lee - 1990 - ntrs.nasa.gov
Reaction rate coefficients and thermodynamic and transport properties are reviewed and
supplemented for the 11-species air model which can be used for analyzing flows in chemical …

Applying probability measures to abstract languages

TL Booth, RA Thompson - IEEE transactions on Computers, 1973 - ieeexplore.ieee.org
The problem of assigning a probability to each word of a language is considered. Two
methods are discussed. One method assigns a probability to a word on the basis of particular …

In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs

RA Thompson, EM Isin, Y Li, L Weidolf… - Chemical research in …, 2012 - ACS Publications
Idiosyncratic adverse drug reactions (IADRs) in humans can result in a broad range of clinically
significant toxicities leading to attrition during drug development as well as postlicensing …

Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies

…, CS Elmore, GN Nilsson, RA Thompson… - Chemical research in …, 2012 - ACS Publications
As part of the drug discovery and development process, it is important to understand the fate
of the drug candidate in humans and the relevance of the animal species used for …

High‐throughput screening of pKa values of pharmaceuticals by pressure‐assisted capillary electrophoresis and mass spectrometry

…, M Englund, MB Någård, RA Thompson - Rapid …, 2003 - Wiley Online Library
A high‐throughput pK a screening method based on pressure‐assisted capillary electrophoresis
(CE) and mass spectrometry (MS) is presented. Effects of buffer type and ionic strength …

Reactive metabolites: current and emerging risk and hazard assessments

RA Thompson, EM Isin, MO Ogese… - Chemical Research …, 2016 - ACS Publications
Although idiosyncratic adverse drug reactions are rare, they are still a major concern to
patient safety. Reactive metabolites are widely accepted as playing a pivotal role in the …

Calculations and curve fits of thermodynamic and transport properties for equilibrium air to 30000 K

RN Gupta, KP Lee, RA Thompson, JM Yos - 1991 - ntrs.nasa.gov
A self-consistent set of equilibrium air values were computed for enthalpy, total specific heat
at constant pressure, compressibility factor, viscosity, total thermal conductivity, and total …

Microbial growth and accumulation in industrial metal-working fluids

…, K Pedersen, N Rodin, RA Thompson… - Applied and …, 1989 - Am Soc Microbiol
The dynamics of microbial growth in metal-working fluids (MWF) and the effect of the addition
of biocides were studied in large fluid systems, in this case, one central tank which holds …

A review of reaction rates and thermodynamic and transport properties for the 11-species air model for chemical and thermal nonequilibrium calculations to 30000 K

RN Gupta, JM Yos, RA Thompson - 1989 - ntrs.nasa.gov
Reaction rate coefficients and thermodynamic and transport properties are provided for the
11-species air model which can be used for analyzing flows in chemical and thermal …

Hypothesis driven drug design: improving quality and effectiveness of the design-make-test-analyse cycle

…, J Kihlberg, J Pettersson, G Robb, RA Thompson - Drug discovery today, 2012 - Elsevier
In drug discovery, the central process of constructing and testing hypotheses, carefully
conducting experiments and analysing the associated data for new findings and information is …