Chemistry, pharmacology, toxicology, and hepatic metabolism of designer drugs of the amphetamine (ecstasy), piperazine, and pyrrolidinophenone types: a synopsis

…, T Kraemer, D Springer, RF Staack - Therapeutic drug …, 2004 - journals.lww.com
Designer drugs of the amphetamine type (eg, MDMA, MDEA, MDA), of the new benzyl or
phenyl piperazine type (eg, BZP, MDBP, mCPP, TFMPP, MeOPP), or of the pyrrolidinophenone …

Screening for and validated quantification of amphetamines and of amphetamine‐and piperazine‐derived designer drugs in human blood plasma by gas …

FT Peters, S Schaefer, RF Staack… - Journal of Mass …, 2003 - Wiley Online Library
The classical stimulants amphetamine, methamphetamine, ethylamphetamine and the
amphetamine‐derived designer drugs MDA, MDMA (‘ecstasy’), MDEA, BDB and MBDB have …

Metabolism of designer drugs of abuse

RF Staack, HH Maurer - Current drug metabolism, 2005 - ingentaconnect.com
Abuse of designer drugs is widespread among young people, especially in the so-called “dance
club scene” or “rave scene”, worldwide. Severe and even fatal poisonings have been …

Analysis of erlotinib and its metabolites in rat tissue sections by MALDI quadrupole time‐of‐flight mass spectrometry

L Signor, E Varesio, RF Staack, V Starke… - Journal of mass …, 2007 - Wiley Online Library
A qualitative and quantitative analysis of erlotinib (RO0508231) and its metabolites was
carried out on rat tissue sections from liver, spleen and muscle. Following oral administration at …

2019 white paper on recent issues in bioanalysis: FDA immunogenicity guidance, gene therapy, critical reagents, biomarkers and flow cytometry validation (part 3 …

…, Q Qu, V Skibeli, TS Saunders, RF Staack… - Bioanalysis, 2019 - Future Science
The 2019 13 th Workshop on Recent Issues in Bioanalysis (WRIB) took place in New
Orleans, LA, USA on April 1–5, 2019 with an attendance of over 1000 representatives from …

2020 White paper on recent issues in bioanalysis: Vaccine assay validation, qPCR assay validation, QC for CAR-T flow cytometry, NAb assay harmonization and …

…, J Pedras-Vasconcelos, M Rajadhyaksha, RF Staack… - Bioanalysis, 2021 - Future Science
The 14 th edition of the Workshop on Recent Issues in Bioanalysis (14 th WRIB) was held
virtually on June 15-29, 2020 with an attendance of over 1000 representatives from …

2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 3–LBA, biomarkers and immunogenicity)

…, J Shih, J Smeraglia, MF Skelly, J Spond, RF Staack… - Bioanalysis, 2015 - Future Science
The 2015 9th Workshop on Recent Issues in Bioanalysis (9th WRIB) took place in Miami,
Florida with participation of 600 professionals from pharmaceutical and biopharmaceutical …

2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3–LBA: immunogenicity …

…, R Neely, M Partridge, RF Staack… - Bioanalysis, 2017 - Future Science
Roland F StaackRoland F Staack … (EU EMA), A Song (Genentech), H Neubert (Pfizer),
F Garofolo (Angelini Pharma) for chairing the workshop and/or the White Paper discussions. All …

2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3–LBA/cell-based assays …

…, C Beaver, G Sperinde, P Siguenza, RF Staack… - Bioanalysis, 2018 - Future Science
The 2018 12 th Workshop on Recent Issues in Bioanalysis took place in Philadelphia, PA,
USA on April 9–13, 2018 with an attendance of over 900 representatives from pharmaceutical/…

Studies on the metabolism and toxicological detection of the new designer drug N-benzylpiperazine in urine using gas chromatography–mass spectrometry

RF Staack, G Fritschi, HH Maurer - Journal of Chromatography B, 2002 - Elsevier
Studies are described on the metabolism and on the toxicological analysis of the piperazine-like
designer drug N-benzylpiperazine (BZP, scene name “A2”) in rat and human urine …