Intact and thoracic duct-cannulated rats were dialyzed at various intraperitoneal pressures
with 5% bovine serum albumin solutions containing 125I-fibrinogen or 51Cr-erythrocytes. …

Twenty-one monkeys (cynomolgus, rhesus, African green) were fed cyclamate (100 mg/kg
and 500 mg/kg) in the diet five times per week from a few days after birth and continuing for …

Publisher Summary This chapter consolidates and quantitates some deleterious effects of
cancer chemotherapeutic agents in humans—namely, their ability to induce chromosomal …

Several group IIIa metal salts, eg, aluminum nitrate, gallium nitrate, indium nitrate, and thallium
chloride, have been evaluated for in vivo toxicity in mice and rats, for cytotoxicity in tumor …

The teratogenic effects of three new plant‐derived antitumor agents, maytansine, VP‐16‐213
and VM‐26, were compared to the effects of vincristine and colchicine in pregnant Swiss …

Background: It was observed in the early 1970s that saccharin produced bladder cancer in
rats. However, it has been unclear whether sodium saccharin when consumed by humans …

The lymphatic absorption and tissue distribution of free [ 14 C]Adriamycin, “empty” [ 3 H]liposomes,
free [ 14 C]Adriamycin plus empty [ 3 H]liposomes, and [ 14 C]Adriamycin entrapped …

The carcinogenic potential of cycasin and methylazoxymethanol (MAM) acetate was
investigated in nonhuman primates. Old-world monkeys (rhesus, cynomolgus, and African green …

… Sieber and Adamson) and Office of the Associate Director (Dr. Mead), Experimental …
KUPCHAN SM. Recent advances in the chemistry of tumor inhibitors of plant origin. Trans …

The carcinogenicity of aflatoxin B 1 (AFB 1 ) has been under evaluation in nonhuman primates
for the past 13 years. A total of 47 Old World monkeys, chiefly rhesus and cynomolgus, …