The in vivo human metabolism of tibolone
RME Vos, SFM Krebbers, CHJ Verhoeven… - Drug metabolism and …, 2002 - ASPET
In vivo metabolism of tibolone was studied in three healthy postmenopausal volunteers after
daily oral administration of 2.5 mg of tibolone for 5 days and a single dose of 2.5 mg ≅ 555 …
daily oral administration of 2.5 mg of tibolone for 5 days and a single dose of 2.5 mg ≅ 555 …
In vitro and in vivo metabolism of desogestrel in several species
CHJ Verhoeven, SFM Krebbers, GN Wagenaars… - Drug metabolism and …, 1998 - ASPET
The metabolism of desogestrel (13-ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol),
an orally active progestogen, was studied in vivo after administration of single oral …
an orally active progestogen, was studied in vivo after administration of single oral …
In vitro and in vivo metabolism of the progestagen Org 30659 in several species
CHJ Verhoeven, SFM Krebbers, GN Wagenaars… - Drug metabolism and …, 1998 - ASPET
The metabolism of Org 30659 [(17α)-17-hydroxy-11-methylene-19-norpregna-4,15-dien-20-yn-3-one],
a new potent progestagen currently under clinical development by NV Organon …
a new potent progestagen currently under clinical development by NV Organon …
Metabolism and excretion of asenapine in healthy male subjects
SFM van de Wetering-Krebbers, PL Jacobs… - Drug metabolism and …, 2011 - ASPET
The metabolism and excretion of asenapine [(3aRS,12bRS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]-oxepino
[4,5-c]pyrrole (2Z)-2-butenedioate (1:1)] were studied …
[4,5-c]pyrrole (2Z)-2-butenedioate (1:1)] were studied …
Absorption, distribution, metabolism and excretion of corifollitropin alfa, a recombinant hormone with a sustained follicle-stimulating activity
A Van Schanke, SFM van De Wetering-Krebbers… - Pharmacology, 2010 - karger.com
The follicle-stimulating hormone (FSH) analog corifollitropin alfa (Org 36286) is a potent
FSH receptor agonist with an extended plasma half-life due to the fusion of the carboxy-terminal …
FSH receptor agonist with an extended plasma half-life due to the fusion of the carboxy-terminal …
IFN‐γ‐induced PD‐L1 expression on human melanocytes is impaired in vitiligo
M Willemsen, G Krebbers, EPM Tjin… - Experimental …, 2022 - Wiley Online Library
… Epidermal cell suspensions were plated in keratinocyte SFM medium (Thermo Fisher
Scientific) supplemented with bovine pituitary extract (Thermo Fisher Scientific), 50 U/mL penicillin …
Scientific) supplemented with bovine pituitary extract (Thermo Fisher Scientific), 50 U/mL penicillin …
Nonclinical efficacy and safety of CX-2029, an Anti-CD71 probody–drug conjugate
…, S Jeffries, S Schleyer, R Leanna, C Krebber… - Molecular Cancer …, 2022 - AACR
… CHO-K1 cells expressing cynomolgus monkey CD71 cells were generated at AbbVie and
grown in Hybridoma SFM + L-glutamine media supplemented with 1% FBS, 1 mmol/L HEPES, …
grown in Hybridoma SFM + L-glutamine media supplemented with 1% FBS, 1 mmol/L HEPES, …
[CITATION][C] Verhoever, CHJ; Delbressine, LPC Drug
RME Vos, SFM Krebbers - Metabol. disposi, 2002
Excretion and metabolism of desogestrel in healthy postmenopausal women
CHJ Verhoeven, RHM Gloudemans… - The Journal of steroid …, 2001 - Elsevier
The metabolism of desogestrel (13-ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol),
a progestagen used in oral contraceptives and hormone replacement therapy, was …
a progestagen used in oral contraceptives and hormone replacement therapy, was …
The in vivo metabolism of tibolone in animal species
CHJ Verhoeven, RME Vos… - European journal of drug …, 2002 - Springer
Thein vivo tissue distribution and metabolism of tibolone was studied in different animals to
further investigate the compound’s tissue-specificity. Tibolone’s metabolism was studiedin …
further investigate the compound’s tissue-specificity. Tibolone’s metabolism was studiedin …