Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
Purpose: The rationale for developing an alternative paclitaxel formulation concerns
Cremophor EL-related side effects, and a novel paclitaxel delivery system might augment its …
Cremophor EL-related side effects, and a novel paclitaxel delivery system might augment its …
Reduced valproic acid serum concentrations due to drug interactions with carbapenem antibiotics: overview of 6 cases
Background: The plasma concentrations of valproic acid (VPA) are known to decrease during
the concomitant administration of carbapenem antibiotics, such as meropenem, imipenem, …
the concomitant administration of carbapenem antibiotics, such as meropenem, imipenem, …
Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers
…, HR Jung, KS Lim, KH Moon, SG Shin… - Clinical …, 2005 - Wiley Online Library
Background Pitavastatin is a potent, newly developed 3‐hydroxy‐3‐methylglutaryl–coenzyme
A reductase inhibitor for the treatment of hyperlipidemia. We characterized the effects of …
A reductase inhibitor for the treatment of hyperlipidemia. We characterized the effects of …
Effect of CYP2C19 polymorphism on the pharmacokinetics of voriconazole after single and multiple doses in healthy volunteers
…, WS Nam, SH Yoon, JY Cho, SG Shin… - The Journal of …, 2012 - Wiley Online Library
The current study assessed the influence of the CYP2C19 genotype on the pharmacokinetics
and tolerability of voriconazole after single and multiple oral doses in healthy volunteers. …
and tolerability of voriconazole after single and multiple oral doses in healthy volunteers. …
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition
…, JY Cho, KS Yu, IJ Jang, SG Shin - Clinical …, 2004 - Wiley Online Library
Background and Objectives There have been considerable disagreements regarding the
influence of MDR1 (ABCB1) polymorphisms on the disposition of P‐glycoprotein (P‐gp) …
influence of MDR1 (ABCB1) polymorphisms on the disposition of P‐glycoprotein (P‐gp) …
Effect of the UGT2B15 Genotype on the Pharmacokinetics, Pharmacodynamics, and Drug Interactions of Intravenous Lorazepam in Healthy Volunteers
…, HR Jung, KS Lim, IJ Jang, SG Shin - Clinical …, 2005 - Wiley Online Library
Objective Our objective was to investigate the effect of the uridine 5′‐diphosphate‐glucuronosyltransferase
(UGT) 2B15 genetic polymorphism on the pharmacokinetics and …
(UGT) 2B15 genetic polymorphism on the pharmacokinetics and …
Apple juice greatly reduces systemic exposure to atenolol
…, I Ieiri, JY Cho, SH Yoon, SG Shin… - British journal of …, 2013 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Atenolol is an antihypertensive drug,
of which negligible amounts are metabolized. • Fruit juices may decrease the oral …
of which negligible amounts are metabolized. • Fruit juices may decrease the oral …
[HTML][HTML] Asian society of gynecologic oncology workshop 2010
…, TS Lee, K Ushijima, SG Shin… - Journal of …, 2010 - synapse.koreamed.org
This workshop was held on July 31-August 1, 2010 and was organized to promote the
academic environment and to enhance the communication among Asian countries prior to the …
academic environment and to enhance the communication among Asian countries prior to the …
Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states
Objective Our objective was to investigate the effect of the CYP3A5 genotype on the systemic
clearance of midazolam in constitutive, inhibited, and induced metabolic conditions. …
clearance of midazolam in constitutive, inhibited, and induced metabolic conditions. …
Incidence of S‐mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics
…, T Ishizaki, SG Shin, IJ Jang, JG Shin… - Clinical …, 1992 - Wiley Online Library
We studied the genetically determined hydroxylation polymorphism of S‐mephenytoin in a
Korean population (N = 206) and the pharmacokinetics of diazepam and demethyldiazepam …
Korean population (N = 206) and the pharmacokinetics of diazepam and demethyldiazepam …