User profiles for Satyanarayana R. Pondugula
Satyanarayana PondugulaProfessor, College of Veterinary Medicine, Auburn University Verified email at auburn.edu Cited by 1111 |
Vitamin D upregulates expression of ECaC1 mRNA in semicircular canal
D Yamauchi, NN Raveendran, SR Pondugula… - Biochemical and …, 2005 - Elsevier
The low luminal Ca 2+ concentration of mammalian endolymph in the vestibular labyrinth is
required for normal balance. We found transcripts in primary cultures of semicircular canal …
required for normal balance. We found transcripts in primary cultures of semicircular canal …
Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response
SR Pondugula, S Mani - Cancer letters, 2013 - Elsevier
Pregnane xenobiotic receptor (PXR) is an orphan nuclear receptor that regulates the metabolism
of endobiotics and xenobiotics. PXR is promiscuous and unique in that it is activated by …
of endobiotics and xenobiotics. PXR is promiscuous and unique in that it is activated by …
[HTML][HTML] Pregnane X receptor and cancer: context-specificity is key
SR Pondugula, P Pavek, S Mani - Nuclear receptor research, 2016 - ncbi.nlm.nih.gov
Pregnane X receptor (PXR) is an adopted orphan nuclear receptor that is activated by a
wide-range of endobiotics and xenobiotics, including chemotherapy drugs. PXR plays a major …
wide-range of endobiotics and xenobiotics, including chemotherapy drugs. PXR plays a major …
Phosphorylation and protein–protein interactions in PXR-mediated CYP3A repression
SR Pondugula, H Dong, T Chen - Expert opinion on drug …, 2009 - Taylor & Francis
Background: The expression of drug-metabolizing enzymes CYPs is controlled by pregnane
X receptor (PXR), and, therefore, understanding how PXR modulates CYP expression is …
X receptor (PXR), and, therefore, understanding how PXR modulates CYP expression is …
A phosphomimetic mutation at threonine-57 abolishes transactivation activity and alters nuclear localization pattern of human pregnane x receptor
SR Pondugula, C Brimer-Cline, J Wu… - Drug metabolism and …, 2009 - ASPET
The pregnane X receptor (PXR) plays crucial roles in multiple physiological processes.
However, the signaling mechanisms responsible are not well defined; it is most likely that …
However, the signaling mechanisms responsible are not well defined; it is most likely that …
Glucocorticoids stimulate cation absorption by semicircular canal duct epithelium via epithelial sodium channel
SR Pondugula, JD Sanneman… - American Journal …, 2004 - journals.physiology.org
The semicircular canal duct (SCCD) epithelium is a vestibular epithelial domain that was
recently shown to actively contribute to endolymph homeostasis by Cl − secretion under control …
recently shown to actively contribute to endolymph homeostasis by Cl − secretion under control …
Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium
…, T Wu, SR Pondugula… - … of Physiology-Cell …, 2009 - journals.physiology.org
Reissner's membrane epithelium forms much of the barrier that produces and sustains the
large ionic differences between cochlear endolymph and perilymph. We have reported that …
large ionic differences between cochlear endolymph and perilymph. We have reported that …
[HTML][HTML] Effects of autologous conditioned serum, autologous protein solution, and triamcinolone on inflammatory and catabolic gene expression in equine cartilage …
Autologous conditioned serum (ACS) and autologous protein solution (APS) are newer
therapeutic options for osteoarthritis (OA). Co-culture of cartilage and synovium stimulated with IL…
therapeutic options for osteoarthritis (OA). Co-culture of cartilage and synovium stimulated with IL…
[HTML][HTML] Oroxylum Indicum ameliorates chemotherapy induced cognitive impairment
While chemotherapy is the most effective therapeutic approach for treating a variety of cancer
patients, commonly used chemotherapeutic agents, often induce several adverse effects. …
patients, commonly used chemotherapeutic agents, often induce several adverse effects. …
Cardioprotective Effects of Oroxylum indicum Extract Against Doxorubicin and Cyclophosphamide-Induced Cardiotoxicity
SR Pondugula, A Harshan, S Ramesh… - Cardiovascular …, 2022 - Springer
Administration of Chemotherapeutics, especially doxorubicin (DOX) and cyclophosphamide
(CPS), is commonly associated with adverse effects such as myelosuppression and …
(CPS), is commonly associated with adverse effects such as myelosuppression and …