Supported by a usage history that predates written records and the perception that “natural”
ensures safety, herbal products have increasingly been incorporated into Western health …

Milk thistle (Silybum marianum) is a popular herbal product used for hepatoprotection and
chemoprevention. Two commercially available formulations are the crude extract, silymarin, …

Despite increasing recognition of potential untoward interactions between herbal products
and conventional medications, a standard system for prospective assessment of these …

Cranberry juice is used routinely, especially among women and the elderly, to prevent and
treat urinary tract infections. These individuals are likely to be taking medications …

Introduction In a pivotal study, apomorphine sublingual film (APL; KYNMOBI ® ) was an
effective and generally well-tolerated on-demand treatment of “OFF” episodes in patients with …

Flavonolignans from milk thistle (Silybum marianum) have been investigated for their cellular
modulatory properties, including cancer chemoprevention and hepatoprotection, as an …

Background Cranberry products have been implicated in several case reports to enhance
the anticoagulant effect of warfarin. The mechanism could involve inhibition of the hepatic …

Napabucasin is an orally administered reactive oxygen species generator that is
bioactivated by the intracellular antioxidant nicotinamide adenine dinucleotide phosphate:quinone …

Azeliragon is an inhibitor of the receptor for advanced glycation end products being developed
for the treatment of Alzheimer's disease. The objective of the current analysis was to …

C. elegans has been widely used as a model organism for programmed cell death and
apoptosis. Although the CED-3 caspase is the primary effector of cell death in C. elegans, no …