Natural deep eutectic solvents: properties, applications, and perspectives
…, JB McAlpine, DC Lankin, SN Chen… - Journal of natural …, 2018 - ACS Publications
As functional liquid media, natural deep eutectic solvent (NADES) species can dissolve natural
or synthetic chemicals of low water solubility. Moreover, the special properties of NADES, …
or synthetic chemicals of low water solubility. Moreover, the special properties of NADES, …
Universal quantitative NMR analysis of complex natural samples
…, JG Napolitano, JB McAlpine, SN Chen… - Current opinion in …, 2014 - Elsevier
Highlights • qNMR is a powerful analytical tool for structure and purity determination. •
qNMR is suitable for the quality control of complex natural samples. • qNMR and MS-hyphenated …
qNMR is suitable for the quality control of complex natural samples. • qNMR and MS-hyphenated …
Importance of Purity Evaluation and the Potential of Quantitative 1H NMR as a Purity Assay: Miniperspective
In any biomedical and chemical context, a truthful description of chemical constitution
requires coverage of both structure and purity. This qualification affects all drug molecules, …
requires coverage of both structure and purity. This qualification affects all drug molecules, …
Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ongoing
coronavirus disease 2019 (COVID-19) pandemic underscores the need for new treatments. …
coronavirus disease 2019 (COVID-19) pandemic underscores the need for new treatments. …
Dentin biomodification: strategies, renewable resources and clinical applications
AK Bedran-Russo, GF Pauli, SN Chen, J McAlpine… - Dental materials, 2014 - Elsevier
Objectives The biomodification of dentin is a biomimetic approach, mediated by bioactive
agents, to enhance and reinforce the dentin by locally altering the biochemistry and …
agents, to enhance and reinforce the dentin by locally altering the biochemistry and …
Countercurrent separation of natural products: an update
JB Friesen, JB McAlpine, SN Chen… - Journal of natural …, 2015 - ACS Publications
This work assesses the current instrumentation, method development, and applications in
countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC), …
countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC), …
Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor
JE Burdette, J Liu, S Chen, DS Fabricant… - Journal of Agricultural …, 2003 - ACS Publications
Extracts of the rhizome of black cohosh [Actaea racemosa L., formerly called Cimicifuga
racemosa (L.) Nutt.] were evaluated for potential mechanisms of action in the alleviation of …
racemosa (L.) Nutt.] were evaluated for potential mechanisms of action in the alleviation of …
Phytochemistry and biological properties of glabridin
Glabridin, a prenylated isoflavonoid of G. glabra L. roots (European licorice, Fabaceae), has
been associated with a wide range of biological properties such as antioxidant, anti-…
been associated with a wide range of biological properties such as antioxidant, anti-…
Can invalid bioactives undermine natural product-based drug discovery?
…, JB McAlpine, JB Friesen, SN Chen… - Journal of medicinal …, 2016 - ACS Publications
High-throughput biology has contributed a wealth of data on chemicals, including natural
products (NPs). Recently, attention was drawn to certain, predominantly synthetic, compounds …
products (NPs). Recently, attention was drawn to certain, predominantly synthetic, compounds …
Sterols from the fungus Lactarium volemus
Seven ergostane-type sterols and two mono-glucosides were isolated from the ethyl acetate
soluble fraction of Lactarium volemus. Three are previously unknown, ie 3-O-β-d-…
soluble fraction of Lactarium volemus. Three are previously unknown, ie 3-O-β-d-…