High levels of intracellular cysteine promote oxidative DNA damage by driving the fenton reaction
S Park, JA Imlay - Journal of bacteriology, 2003 - Am Soc Microbiol
Escherichia coli is generally resistant to H 2 O 2 , with >75% of cells surviving a 3-min challenge
with 2.5 mM H 2 O 2 . However, when cells were cultured with poor sulfur sources and …
with 2.5 mM H 2 O 2 . However, when cells were cultured with poor sulfur sources and …
Substantial DNA damage from submicromolar intracellular hydrogen peroxide detected in Hpx- mutants of Escherichia coli
S Park, X You, JA Imlay - Proceedings of the National …, 2005 - National Acad Sciences
Since the discovery of catalase, it has been postulated that aerobic organisms generate
enough oxidants to threaten their own fitness and, in particular, their genetic stability. An …
enough oxidants to threaten their own fitness and, in particular, their genetic stability. An …
Factors Contributing to Hydrogen Peroxide Resistance in Streptococcus pneumoniae Include Pyruvate Oxidase (SpxB) and Avoidance of the Toxic Effects of the …
CD Pericone, S Park, JA Imlay… - Journal of bacteriology, 2003 - Am Soc Microbiol
Aerobic growth of Streptococcus pneumoniae results in production of amounts of hydrogen
peroxide (H 2 O 2 ) that may exceed 1 mM in the surrounding media. H 2 O 2 production by S…
peroxide (H 2 O 2 ) that may exceed 1 mM in the surrounding media. H 2 O 2 production by S…
Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: Studies in vitro, in animals, and in humans
…, RA Neese, K Haddock, SS Park… - Proceedings of the …, 1998 - National Acad Sciences
A method for measuring DNA synthesis and, thus, cell proliferation, in vivo is presented. The
technique consists of administering [6,6- 2 H 2 ]Glc or [U- 13 C]Glc, isolating genomic DNA, …
technique consists of administering [6,6- 2 H 2 ]Glc or [U- 13 C]Glc, isolating genomic DNA, …
Nuances in the management of rhinophyma
…, FJ Stucker, A Compton, SS Park - Facial Plastic …, 2012 - thieme-connect.com
Rhinophyma is a cosmetically disfiguring disease of the external nose that most frequently
affects elderly Caucasian males. Frequently, there is associated derangement of nasal airway …
affects elderly Caucasian males. Frequently, there is associated derangement of nasal airway …
Submicromolar hydrogen peroxide disrupts the ability of Fur protein to control free‐iron levels in Escherichia coli
S Varghese, A Wu, S Park, KRC Imlay… - Molecular …, 2007 - Wiley Online Library
In aerobic environments, mutants of Escherichia coli that lack peroxidase and catalase
activities (Hpx – ) accumulate submicromolar concentrations of intracellular H 2 O 2 . We …
activities (Hpx – ) accumulate submicromolar concentrations of intracellular H 2 O 2 . We …
Defects in Innate Immunity Predispose C57BL/6J-Leprdb/Leprdb Mice to Infection by Staphylococcus aureus
S Park, J Rich, F Hanses, JC Lee - Infection and immunity, 2009 - Am Soc Microbiol
Foot and ankle infections are the most common cause of hospitalization among diabetic
patients, and Staphylococcus aureus is a major pathogen implicated in these infections. …
patients, and Staphylococcus aureus is a major pathogen implicated in these infections. …
[HTML][HTML] Reduced neutrophil apoptosis in diabetic mice during staphylococcal infection leads to prolonged Tnfα production and reduced neutrophil clearance
F Hanses, S Park, J Rich, JC Lee - PloS one, 2011 - journals.plos.org
Diabetes is a frequent underlying medical condition among individuals with Staphylococcus
aureus infections, and diabetic patients often suffer from chronic inflammation and …
aureus infections, and diabetic patients often suffer from chronic inflammation and …
Large litter rearing enhances leptin sensitivity and protects selectively bred diet-induced obese rats from becoming obese
CM Patterson, SG Bouret, S Park, BG Irani… - …, 2010 - academic.oup.com
Because rearing rats in large litters (LLs) protects them from becoming obese, we postulated
that LL rearing would protect rats selectively bred to develop diet-induced obesity (DIO) …
that LL rearing would protect rats selectively bred to develop diet-induced obesity (DIO) …
[HTML][HTML] Community pharmacists' knowledge, perceptions, and practices about topical corticosteroid counseling: A real-world cross-sectional survey and focus group …
MJ Kang, JH Park, S Park, NG Kim, EY Kim, YM Yu… - PLoS …, 2020 - journals.plos.org
Topical corticosteroids (TCs) are widely used to treat dermatological conditions such as
eczema and psoriasis. It can be a safe and effective treatment when used appropriately. …
eczema and psoriasis. It can be a safe and effective treatment when used appropriately. …