Cytochromes P-450 are ubiquitous in nature. The levels of these hemoproteins can be
influenced by many chemicals and the enzymes in turn are capable of me-tabolizing many …

Sphingosine 1-phosphate (S1P), a multifunctional lipid mediator, regulates lymphocyte
trafficking, vascular permeability, and angiogenesis by activation of the S1P 1 receptor. This …

Aluminum ion has been proposed to be a. factor contributing to the toxicily of aquatic acidif~-tion
caused by acid rain, and to the etiology of a variety of neurological and skeletal …

Class III beta-tubulin, isolated from adult bovine brain, is resolved into at least seven charge
variants on isoelectric focusing gels. To identify the posttranslational modifications …

Sphingosine 1-phosphate (S1P) is a lysophospholipid mediator that evokes a variety of cell
and tissue responses via a set of cell surface receptors. The recent development of S1P …

The mechanisms involved in renal ischemia-reperfusion injury (IRI) are complex and appear
to involve the early participation of bone marrow-derived cells. T lymphocytes participate in …

Immunotherapeutic drugs that mimic sphingosine 1-phosphate (S1P) disrupt lymphocyte
trafficking and cause T helper and T effector cells to be retained in secondary lymphoid tissue …

We sought to determine the mechanisms responsible for the reduced renal tissue injury by
agonists of A 2A adenosine receptors (A 2A -ARs) in models of ischemia-reperfusion (I/R) …

The synthesis of N-arylamide phosphonates and related arylether and arylamine analogues
provided potent, subtype-selective agonists and antagonists of the five known sphingosine 1…

Cytochrome P‐450 (P‐450) enzymes catalyze the oxidation of a wide variety of substrates.
Although a large number of P‐450s have been characterized in different species and tissues, …