User profiles for U Hofmann
Ulrich G. HofmannUniversity Medical Center Freiburg Verified email at uniklinik-freiburg.de Cited by 4144 |
[HTML][HTML] Matrix metalloproteinases in human melanoma
UB Hofmann, JR Westphal, GNP van Muijen… - Journal of Investigative …, 2000 - Elsevier
Cutaneous melanoma is a highly invasive and metastatic tumor. Degradation of basement
membranes and extracellular matrix is an essential step in melanoma cell migration, invasion, …
membranes and extracellular matrix is an essential step in melanoma cell migration, invasion, …
[HTML][HTML] A comprehensive guide for the recognition and classification of distinct stages of hair follicle morphogenesis
…, M Maurer, S Eichmüller, G Ling, U Hofmann… - Journal of Investigative …, 1999 - Elsevier
… Stage 7, days 4–5 pp (U) tip of the hair shaft leaves the epidermis (a) in the close vicinity
of the infundibulum of the SG (b). (V) the tip of the hair shaft (a) leaves the TGF-β-RII-negative …
of the infundibulum of the SG (b). (V) the tip of the hair shaft (a) leaves the TGF-β-RII-negative …
Role of lymphocytes in myocardial injury, healing, and remodeling after myocardial infarction
U Hofmann, S Frantz - Circulation research, 2015 - Am Heart Assoc
A large body of evidence produced during decades of research indicates that myocardial
injury activates innate immunity. On the one hand, innate immunity both aggravates ischemic …
injury activates innate immunity. On the one hand, innate immunity both aggravates ischemic …
Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver
…, AK Nüssler, P Neuhaus, U Hofmann… - Pharmacogenetics …, 2001 - journals.lww.com
The human cytochrome P450, CYP2B6, is involved in the metabolism of several therapeutically
important drugs and environmental or abused toxicants. In this study, we present the first …
important drugs and environmental or abused toxicants. In this study, we present the first …
Foxp3+ CD4+ T Cells Improve Healing After Myocardial Infarction by Modulating Monocyte/Macrophage Differentiation
J Weirather, UDW Hofmann, N Beyersdorf… - Circulation …, 2014 - Am Heart Assoc
Rationale: An exaggerated or persistent inflammatory activation after myocardial infarction (MI)
leads to maladaptive healing and subsequent remodeling of the left ventricle. Foxp3 + …
leads to maladaptive healing and subsequent remodeling of the left ventricle. Foxp3 + …
[PDF][PDF] Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group
…, J Blievernicht, J Fischer, U Hofmann… - Journal of clinical …, 2008 - academia.edu
Purpose To assess the predictive value of polymorphisms in dihydropyrimidine dehydrogenase
(DPYD), thymidylate synthase (TYMS), and methylene tetrahydrofolate reductase (…
(DPYD), thymidylate synthase (TYMS), and methylene tetrahydrofolate reductase (…
[PDF][PDF] Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma
…, P Franco, M Khiat, J Zhang, UG Hofmann… - Cancer cell, 2022 - cell.com
… Hofmann,2… Significance was determined using Mann-Whitney U test, and p values were
corrected … , MP, Takahashi, F., Maheswaran, S., McDermott, U., Azizian, N., Zou, L., Fischbach, …
corrected … , MP, Takahashi, F., Maheswaran, S., McDermott, U., Azizian, N., Zou, L., Fischbach, …
Activation of CD4+ T Lymphocytes Improves Wound Healing and Survival After Experimental Myocardial Infarction in Mice
U Hofmann, N Beyersdorf, J Weirather, A Podolskaya… - Circulation, 2012 - Am Heart Assoc
… Proliferation/antigen recall assays were performed in 96-well U-bottom plates. A total of 2×10
5 lymph node cells per well were diluted in a final volume of 200 μL. All cultures were …
5 lymph node cells per well were diluted in a final volume of 200 μL. All cultures were …
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity
…, K Hoshitsuki, J Nersting, K Kihira, U Hofmann… - Nature …, 2016 - nature.com
Widely used as anticancer and immunosuppressive agents, thiopurines have narrow therapeutic
indices owing to frequent toxicities, partly explained by TPMT genetic polymorphisms. …
indices owing to frequent toxicities, partly explained by TPMT genetic polymorphisms. …
[HTML][HTML] T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10
… (10 U/µl), and 3.5 µl Ribonuclease H (2 U/µl) were added to the cleaved sample and incubated
at 16 C for 2 h. Eppendorf tubes were placed on ice and 5 µl of T4 DNA polymerase (3 U/…
at 16 C for 2 h. Eppendorf tubes were placed on ice and 5 µl of T4 DNA polymerase (3 U/…