Diet-induced obesity in male mice is associated with reduced fertility and potentiation of acrylamide-induced reproductive toxicity
…, R Bai, GE Kissling, G Travlos, U Hoffler - Biology of …, 2010 - academic.oup.com
The prevalence of human obesity and related chronic disorders such as diabetes,
cardiovascular diseases, and cancer is rapidly increasing. Human studies have shown a direct …
cardiovascular diseases, and cancer is rapidly increasing. Human studies have shown a direct …
[HTML][HTML] COVID-19 vaccine hesitancy in underserved communities of North Carolina
…, W Pilkington, L Brown, V Billings, U Hoffler… - PLoS …, 2021 - journals.plos.org
Background In the United States, underserved communities including Blacks and Latinx are
disproportionately affected by COVID-19. This study sought to estimate the prevalence of …
disproportionately affected by COVID-19. This study sought to estimate the prevalence of …
Diet-induced obesity is associated with hyperleptinemia, hyperinsulinemia, hepatic steatosis, and glomerulopathy in C57Bl/6J mice
U Hoffler, K Hobbie, R Wilson, R Bai, A Rahman… - Endocrine, 2009 - Springer
Obesity and obesity-related illnesses are global epidemics impacting the health of adults and
children. The purpose of the present work is to evaluate a genetically intact obese mouse …
children. The purpose of the present work is to evaluate a genetically intact obese mouse …
Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect
BI Ghanayem, KL Witt, L El-Hadri, U Hoffler… - Biology of …, 2005 - academic.oup.com
Acrylamide is an animal carcinogen and probable human carcinogen present in appreciable
amounts in heated carbohydrate-rich foodstuffs. It is also a germ cell mutagen, inducing …
amounts in heated carbohydrate-rich foodstuffs. It is also a germ cell mutagen, inducing …
Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using cyp2e1-/-mice
BI Ghanayem, U Hoffler - Current drug metabolism, 2007 - ingentaconnect.com
Cytochromes P450 (CYPs) comprise a number of enzyme subfamilies responsible for the
oxidative metabolism of a wide range of therapeutic agents, environmental toxicants, mutagens…
oxidative metabolism of a wide range of therapeutic agents, environmental toxicants, mutagens…
Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
U Hoffler, HA El-Masri, BI Ghanayem - Journal of Pharmacology and …, 2003 - ASPET
Urethane ([carbonyl- 14 C]ethyl carbamate) is a fermentation by-product in alcoholic beverages
and foods and is classified as reasonably anticipated to be a human carcinogen. Early …
and foods and is classified as reasonably anticipated to be a human carcinogen. Early …
Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice
U Hoffler, D Dixon, S Peddada, BI Ghanayem - … Research/Fundamental and …, 2005 - Elsevier
Urethane is a multi-site animal carcinogen and was classified as “reasonably anticipated to
be a human carcinogen.” Urethane is a fermentation by-product and found at appreciable …
be a human carcinogen.” Urethane is a fermentation by-product and found at appreciable …
[PDF][PDF] COVID-19 testing and barriers to vaccine hesitancy in the Lumbee Tribe of North Carolina
…, P Strickland, WF Pilkington, U Hoffler… - North Carolina …, 2021 - academia.edu
During the COVID-19 pandemic, the North Carolina Central University Advanced Center for
COVID-19 Related Disparities (ACCORD), the Lumbee Tribe of North Carolina, and the …
COVID-19 Related Disparities (ACCORD), the Lumbee Tribe of North Carolina, and the …
Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice
U Hoffler, BI Ghanayem - Drug metabolism and disposition, 2005 - ASPET
Urethane is a fermentation by-product and a potent animal carcinogen. Human exposure to
urethane occurs through consumption of alcoholic beverages and fermented foods. Recently…
urethane occurs through consumption of alcoholic beverages and fermented foods. Recently…
Stress First Aid for Health-care Workers: An Indicated Mental Illness Prevention Program for Nursing Education
SP Convoy, M Heflin, BM Alston, U Hoffler… - Nursing …, 2023 - nursing.theclinics.com
According to a survey published by Mental Health America and funded by the Johnson &
Johnson Foundation, 93% of health-care workers are experiencing clinically significant and …
Johnson Foundation, 93% of health-care workers are experiencing clinically significant and …