THE CD40 surface molecule is a 277-amino-acid glycoprotein expressed on B lymphocytes,
epithelial cells and some carcinoma cell lines. Monoclonal antibodies against CD40 …

A cDNA encoding human IL-17 (hIL-17) was cloned from a CD4+ T cell library. The predicted
155-amino acids sequence contains an N-terminal signal peptide and exhibits 72% amino …

Herpesvirus Saimiri gene 13 (HVS13) exhibits 57% identity with the predicted sequence of
a T cell-derlved molecule termed CTLAI. Recombinant HVS13 and CTLA8 stimulate …

The ligand for CD40 (CD40L) is a membrane glycoprotein on activated T cells that induces
B cell proliferation and immunoglobulin secretion. Abnormalities in the CD40L gene were …

CD40 is a member of the tumor necrosis factor (TNF) receptor family of cell surface proteins
and was originally described as a B cell restricted antigen. Treatment of primary human …

Cultured human umbilical vein endothelial cells (EC) constitutively express a low level of
CD40 antigen as detected by monoclonal antibody binding and fluorescence flow cytometric …

TWEAK is a member of the TNF ligand family that induces angiogenesis in vivo. We report
cloning of a receptor for TWEAK (TweakR) from a human umbilical vein endothelial cell (…

4‐1BB is an inducible T cell antigen that shows sequence homology to members of an emerging
family of cytokine receptors, including those for tumor necrosis factor and nerve growth …

IL-17 is a T cell-derived cytokine that stimulates stromal cells and macrophages to secrete
proinflammatory cytokines. We hypothesized that IL-17 might play a role in alloimmune …

CD39, a 70- to 100-kDa molecule expressed primarily on activated lymphoid cells, was
previously shown to mediate B cell homotypic adhesion when ligated with a subset of anti-CD39 …