Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model
XJ Tian, XW Yang, X Yang, K Wang - International journal of pharmaceutics, 2009 - Elsevier
To investigate the structure–permeability relationship of dietary/nutriceutic flavonoids, the
transepithelial transport and cellular uptake of 36 flavonoids (including flavones, flavonols, …
transepithelial transport and cellular uptake of 36 flavonoids (including flavones, flavonols, …
Vanadium compounds induced mitochondria permeability transition pore (PTP) opening related to oxidative stress
Y Zhao, L Ye, H Liu, Q Xia, Y Zhang, X Yang… - Journal of inorganic …, 2010 - Elsevier
Vanadium compounds have been regarded as promising in therapeutic treatment of
diabetes and in cancer prevention. In the present work, we studied the effects of vanadium …
diabetes and in cancer prevention. In the present work, we studied the effects of vanadium …
Structure and function of S-adenosylhomocysteine hydrolase
MA Turner, X Yang, D Yin, K Kuczera… - Cell biochemistry and …, 2000 - Springer
In mammals, S-adenosylhomocysteine hydrolase (AdoHcyase) is the only known enzyme to
catalyze the breakdown of S-adenosylhomocysteine (AdoHcy) to homocysteine and …
catalyze the breakdown of S-adenosylhomocysteine (AdoHcy) to homocysteine and …
Gadolinium‐induced oxidative stress triggers endoplasmic reticulum stress in rat cortical neurons
Q Xia, X Feng, H Huang, L Du, X Yang… - Journal of …, 2011 - Wiley Online Library
J. Neurochem. (2011) 117, 38–47. Abstract Introduction of Gadolinium (Gd) to the nervous
system is linked to the development of neurotoxicity involving both oxidative and endoplasmic …
system is linked to the development of neurotoxicity involving both oxidative and endoplasmic …
La3+, Gd3+ and Yb3+ induced changes in mitochondrial structure, membrane permeability, cytochrome c release and intracellular ROS level
H Liu, L Yuan, X Yang, K Wang - Chemico-biological interactions, 2003 - Elsevier
Lanthanides (Ln) were known to induce cell apoptosis, which might be the results of their
effects on mitochondria (MT). This study was trying to clarify the role of MT and reactive oxygen …
effects on mitochondria (MT). This study was trying to clarify the role of MT and reactive oxygen …
Impaired mitochondrial function and oxidative stress in rat cortical neurons: implications for gadolinium-induced neurotoxicity
X Feng, Q Xia, L Yuan, X Yang, K Wang - Neurotoxicology, 2010 - Elsevier
Gadolinium (Gd), a rare-earth lanthanides metal, is widely utilized for various industrial and
medical purposes, particularly in brain magnetic resonance imaging. However, its potential …
medical purposes, particularly in brain magnetic resonance imaging. However, its potential …
Absorption and metabolism of Astragali radix decoction: in silico, in vitro, and a case study in vivo
F Xu, Y Zhang, S Xiao, X Lu, D Yang, X Yang… - Drug Metabolism and …, 2006 - ASPET
To profile absorption of Astragali Radix decoction and identify its orally absorbable constituents
and their metabolites, four complementary in silico, in vitro, and in vivo methods, ie, a …
and their metabolites, four complementary in silico, in vitro, and in vivo methods, ie, a …
Catalytic Strategy of S-Adenosyl-l-homocysteine Hydrolase: Transition-State Stabilization and the Avoidance of Abortive Reactions
X Yang, Y Hu, DH Yin, MA Turner, M Wang… - Biochemistry, 2003 - ACS Publications
S-Adenosylhomocysteine hydrolase (AdoHcy hydrolase) crystallizes from solutions containing
the intermediate analogue neplanocin A with the analogue bound in its 3‘-keto form at the …
the intermediate analogue neplanocin A with the analogue bound in its 3‘-keto form at the …
Folic acid reverses hyper-responsiveness of LPS-induced chemokine secretion from monocytes in patients with hyperhomocysteinemia
G Wang, J Dai, J Mao, X Zeng, X Yang, X Wang - Atherosclerosis, 2005 - Elsevier
Our previous study demonstrated that homocysteine (Hcy) mediated the expression and
secretion of MCP-1 and IL-8 in human monocytes. In the present study, we investigated whether …
secretion of MCP-1 and IL-8 in human monocytes. In the present study, we investigated whether …
The molecular mechanisms and rational design of anti-diabetic vanadium compounds
…, Z Wang, Y Zhang, Q Xia, X Yang - Current topics in …, 2016 - ingentaconnect.com
Vanadium compounds are promising anti-diabetic agents. Although BEOV was not able to
succeed in phase II clinical trial, great progresses have been made in the past three decades …
succeed in phase II clinical trial, great progresses have been made in the past three decades …