Breed differences in boar taint: relationship between tissue levels boar taint compounds and sensory analysis of taint

…, EE Holton, Z Vickers, EJ Squires, Y Lou… - Journal of animal …, 1996 - academic.oup.com
A total of 228 intact male pigs from Duroc, Hampshire, Landrace, and Yorkshire breeds were
used in the experiment. Samples of salivary gland and backfat were collected at slaughter …

Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels

Z Lin, Y Lou, EJ Squires - The Journal of Steroid Biochemistry and …, 2006 - Elsevier
Raising intact male pigs would have a significant economic impact on the pork industry.
However, the presence of skatole (a major cause of boar taint) in meat from intact male pigs …

Molecular cloning and functional analysis of porcine SULT1A1 gene and its variant: a single mutation SULT1A1 causes a significant decrease in sulfation activity

Z Lin, Y Lou, JE Squires - Mammalian genome, 2004 - Springer
The characterization of the SULT1A1 gene and its variants should have an important impact
on the efforts to develop genetic markers to select for low skatole in pigs. Raising intact male …

[HTML][HTML] Dietary Fermentation Product of Aspergillus Oryzae Prevents Increases in Gastrointestinal Permeability ('Leaky Gut') in Horses Undergoing Combined …

…, S Manley, A Aho, KN Heeringa, L Whitacre, Y Lou… - Animals, 2023 - mdpi.com
Simple Summary Equine leaky gut syndrome is characterized by gastrointestinal hyperpermeability
and may be associated with adverse health effects in horses. The purpose was to …

A novel polymorphism in the 5′ untranslated region of theporcine cytochrome b5 (CYB5) gene is associated with decreased fat androstenone level

Z Lin, Y Lou, J Peacock, EJ Squires - Mammalian genome, 2005 - Springer
Raising intact male pigs would have a significant economic impact on the pork industry;
however, the presence of 16-androstene (a major cause of boar taint) in meat from male pigs …

The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes

MA Terner, WJ Gilmore, Y Lou, EJ Squires - Drug Metabolism and …, 2006 - ASPET
The accumulation of 3-methylindole (3MI) in uncastrated male pigs (boars) is a major cause
of boar taint, which negatively affects the quality of meat from the animal. Previously, …

A comparative investigation of the effects of feed-borne deoxynivalenol (DON) on growth performance, nutrient utilization and metabolism of detoxification in rainbow …

JM Hooft, P Wu, CD Powell, Y Lou, EJ Squires, JP Cant… - Aquaculture, 2019 - Elsevier
Increasing evidence suggests that variability in hepatic glucuronidation is a critical determinant
of mammalian species-specific sensitivity to the Fusarium mycotoxin deoxynivalenol (…

Effect of mutations in porcine CYB5A and CYP17A1 on the metabolism of pregnenolone

EJ Squires, MA Gray, Y Lou - The Journal of Steroid Biochemistry and …, 2019 - Elsevier
Cytochrome P450 17A1 (CYP17A1) catalyses the 17α-hydroxylation and 17,20 lyase reactions
to convert pregnenolone to 17α-hydroxypregnenolone (17OHP) and subsequently the …

Sulfiredoxin involved in the protection of peroxiredoxins against hyperoxidation in the early hyperglycaemia

S Shi, Y Guo, Y Lou, Q Li, X Cai, X Zhong… - Experimental Cell …, 2017 - Elsevier
As a direct consequence of hyperglycaemia, the excessive generation of ROS is central to the
pathogenesis of diabetic cardiomyopathy. We hypothesize that stimulation of high glucose …

The characterization of androstenone transport in boar plasma

C Bone, C Anderson, Y Lou, EJ Squires - The Journal of Steroid …, 2019 - Elsevier
The transport of steroids by plasma proteins influences the amount of steroid available for
uptake by the target tissue. In the boar, androstenone is transported to the adipose tissue …