We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression
of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that …

10.7554/eLife.04577.001 We identified the neurons comprising the Drosophila mushroom
body (MB), an associative center in invertebrate brains, and provide a comprehensive map …

10.7554/eLife.04580.001 Animals discriminate stimuli, learn their predictive value and use
this knowledge to modify their behavior. In Drosophila, the mushroom body (MB) plays a key …

Animals approach stimuli that predict a pleasant outcome 1 . After the paired presentation of
an odour and a reward, Drosophila melanogaster can develop a conditioned approach …

The mushroom body is required for a variety of behaviors of Drosophila melanogaster.
Different types of intrinsic and extrinsic mushroom body neurons might underlie its functional …

For many antibodies, each antigen-binding site binds to only one antigen molecule during
the antibody's lifetime in plasma. To increase the number of cycles of antigen binding and …

Making inferences about the computations performed by neuronal circuits from synapse-level
connectivity maps is an emerging opportunity in neuroscience. The mushroom body (MB) …

Synaptic activity can boost neuroprotection through a mechanism that requires synapse-to-nucleus
communication and calcium signals in the cell nucleus. Here we show that in …

10.7554/eLife.26975.001 Understanding memory formation, storage and retrieval requires
knowledge of the underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the …

Animals acquire predictive values of sensory stimuli through reinforcement. In the brain of
Drosophila melanogaster, activation of two types of dopamine neurons in the PAM and PPL1 …